hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01542
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PCBD2 | Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) | UniProt NCBI |
| CKB | Creatine kinase B-type (EC 2.7.3.2) (Brain creatine kinase) (B-CK) (Creatine kinase B chain) (Creatine phosphokinase B-type) (CPK-B) | UniProt NCBI |
| NPEPPS | Puromycin-sensitive aminopeptidase (PSA) (EC 3.4.11.14) (Cytosol alanyl aminopeptidase) (AAP-S) | UniProt NCBI |
| CKM | Creatine kinase M-type (EC 2.7.3.2) (Creatine kinase M chain) (Creatine phosphokinase M-type) (CPK-M) (M-CK) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-71288 | 0.000281403908969 | 0.5 | CKM CKB | Creatine metabolism |
| WP:WP497 | 0.000352218401684 | 0.5 | CKM CKB | Urea cycle and metabolism of amino groups |
| KEGG:00330 | 0.00225083015122 | 0.5 | CKM CKB | Arginine and proline metabolism |
| GO:0006599 | 0.0270421395626 | 0.5 | CKM CKB | phosphagen metabolic process |
| GO:0006603 | 0.0270421395626 | 0.5 | CKM CKB | phosphocreatine metabolic process |
| GO:0042396 | 0.0270421395626 | 0.5 | CKM CKB | phosphagen biosynthetic process |
| GO:0046314 | 0.0270421395626 | 0.5 | CKM CKB | phosphocreatine biosynthetic process |
| GO:0004111 | 0.0405595771497 | 0.5 | CKM CKB | creatine kinase activity |
| GO:0016775 | 0.0405595771497 | 0.5 | CKM CKB | phosphotransferase activity, nitrogenous group as acceptor |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CKB | CKM | 0.75 | 0.743 | bioplex (CKB,CKM) bioplex_WMM |
| CKM | NPEPPS | 0.646 | 0.686 | fraction |
| CKB | NPEPPS | 0.215 | 0.464 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| PCBD2 | CKM | 0.029 | 0.23 | fraction |
| PCBD2 | CKB | 0.027 | 0.231 | fraction |
Images
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Complex HuMAP2_01542 has an average edge precision of 0.471 which is ranked 2693 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PCBD2 | HuMAP2_00869 HuMAP2_01542 HuMAP2_04093 HuMAP2_06767 |
| CKB | HuMAP2_01001 HuMAP2_01415 HuMAP2_01542 |
| NPEPPS | HuMAP2_01542 HuMAP2_06795 |
| CKM | HuMAP2_01415 HuMAP2_01542 HuMAP2_06795 |