hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01543
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SPTAN1 | Spectrin alpha chain, non-erythrocytic 1 (Alpha-II spectrin) (Fodrin alpha chain) (Spectrin, non-erythroid alpha subunit) | UniProt NCBI |
| OSBP | Oxysterol-binding protein 1 | UniProt NCBI |
| FEN1 | Flap endonuclease 1 (FEN-1) (EC 3.1.-.-) (DNase IV) (Flap structure-specific endonuclease 1) (Maturation factor 1) (MF1) (hFEN-1) | UniProt NCBI |
| SPTB | Spectrin beta chain, erythrocytic (Beta-I spectrin) | UniProt NCBI |
| GCSH | Glycine cleavage system H protein, mitochondrial (Lipoic acid-containing protein) | UniProt NCBI |
| TPM3 | Tropomyosin alpha-3 chain (Gamma-tropomyosin) (Tropomyosin-3) (Tropomyosin-5) (hTM5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-445095 | 0.00895825109095 | 0.333333333333 | SPTAN1 SPTB | Interaction between L1 and Ankyrins |
| REAC:R-HSA-375165 | 0.0269276420577 | 0.333333333333 | SPTAN1 SPTB | NCAM signaling for neurite out-growth |
| CORUM:7282 | 0.0499726005494 | 0.166666666667 | FEN1 | FEN1-WRN complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SPTAN1 | TPM3 | 0.649 | 0.688 | hein_WMM bioplex (TPM3) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| SPTAN1 | SPTB | 0.533 | 0.638 | bioplex_WMM fraction |
| SPTAN1 | GCSH | 0.171 | 0.429 | bioplex_WMM fraction |
| TPM3 | GCSH | 0.158 | 0.416 | bioplex_WMM fraction |
| SPTAN1 | FEN1 | 0.087 | 0.353 | bioplex (FEN1) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| SPTAN1 | OSBP | 0.054 | 0.3 | gupta_WMM fraction treiber_WMM |
| OSBP | TPM3 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| SPTB | TPM3 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| FEN1 | OSBP | 0.007 | 0.002 | bioplex_WMM youn_WMM WMM_only |
| FEN1 | TPM3 | 0.0 | 0.005 | bioplex (FEN1) bioplex_WMM youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| OSBP | GCSH | 0.0 | 0.009 | fraction |
Images
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Complex HuMAP2_01543 has an average edge precision of 0.258 which is ranked 5252 out of all 6965 complexes.
Related Complexes