hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01554
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NFIA | Nuclear factor 1 A-type (NF1-A) (Nuclear factor 1/A) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/A) (NF-I/A) (NFI-A) (TGGCA-binding protein) | UniProt NCBI |
| NFIX | Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein) | UniProt NCBI |
| NFIB | Nuclear factor 1 B-type (NF1-B) (Nuclear factor 1/B) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/B) (NF-I/B) (NFI-B) (TGGCA-binding protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-73980 | 7.96236129391e-07 | 1.0 | NFIX NFIA NFIB | RNA Polymerase III Transcription Termination |
| REAC:R-HSA-749476 | 4.79270307132e-06 | 1.0 | NFIX NFIA NFIB | RNA Polymerase III Abortive And Retractive Initiation |
| REAC:R-HSA-74158 | 4.79270307132e-06 | 1.0 | NFIX NFIA NFIB | RNA Polymerase III Transcription |
| HP:0100729 | 0.00060627869577 | 1.0 | NFIX NFIA NFIB | Large face |
| HP:0000463 | 0.00831289078327 | 1.0 | NFIX NFIA NFIB | Anteverted nares |
| HP:0005288 | 0.00901503471868 | 1.0 | NFIX NFIA NFIB | Abnormality of the nares |
| HP:0000429 | 0.0126654873819 | 1.0 | NFIX NFIA NFIB | Abnormality of the nasal alae |
| HP:0000965 | 0.0156055992881 | 0.666666666667 | NFIX NFIA | Cutis marmorata |
| HP:0000177 | 0.0192028815334 | 1.0 | NFIX NFIA NFIB | Abnormality of upper lip |
| MIRNA:hsa-miR-6801-3p | 0.0222508235814 | 0.666666666667 | NFIX NFIB | hsa-miR-6801-3p |
| MIRNA:hsa-miR-6810-3p | 0.0222508235814 | 0.666666666667 | NFIX NFIB | hsa-miR-6810-3p |
| HP:0010938 | 0.0316591597185 | 1.0 | NFIX NFIA NFIB | Abnormality of the external nose |
| HP:0000290 | 0.0351100068041 | 1.0 | NFIX NFIA NFIB | Abnormality of the forehead |
| HP:0003745 | 0.0360542445711 | 0.666666666667 | NFIX NFIA | Sporadic |
| HP:0000159 | 0.0373891909751 | 1.0 | NFIX NFIA NFIB | Abnormal lip morphology |
| HP:0005105 | 0.0373891909751 | 1.0 | NFIX NFIA NFIB | Abnormal nasal morphology |
| MIRNA:hsa-miR-223-3p | 0.0393704925026 | 0.666666666667 | NFIX NFIA | hsa-miR-223-3p |
| HP:0001999 | 0.0448141259844 | 1.0 | NFIX NFIA NFIB | Abnormal facial shape |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NFIA | NFIB | 0.984 | 0.899 | bioplex (NFIB) bioplex_WMM youn_WMM gupta_WMM |
| NFIX | NFIB | 0.913 | 0.836 | bioplex (NFIB) bioplex_WMM |
| NFIA | NFIX | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01554 has an average edge precision of 0.61 which is ranked 1892 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NFIA | HuMAP2_01554 HuMAP2_03352 |
| NFIX | HuMAP2_01554 HuMAP2_03352 |
| NFIB | HuMAP2_01554 HuMAP2_03352 |