hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01555
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| LIN7B | Protein lin-7 homolog B (Lin-7B) (hLin7B) (Mammalian lin-seven protein 2) (MALS-2) (Vertebrate lin-7 homolog 2) (Veli-2) (hVeli2) | UniProt NCBI |
| LIN7A | Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1) | UniProt NCBI |
| TCEAL4 | Transcription elongation factor A protein-like 4 (TCEA-like protein 4) (Transcription elongation factor S-II protein-like 4) | UniProt NCBI |
| USP11 | Ubiquitin carboxyl-terminal hydrolase 11 (EC 3.4.19.12) (Deubiquitinating enzyme 11) (Ubiquitin thioesterase 11) (Ubiquitin-specific-processing protease 11) | UniProt NCBI |
| CDA | Cytidine deaminase (EC 3.5.4.5) (Cytidine aminohydrolase) | UniProt NCBI |
| MPP6 | MAGUK p55 subfamily member 6 (Veli-associated MAGUK 1) (VAM-1) | UniProt NCBI |
| MPP2 | MAGUK p55 subfamily member 2 (Discs large homolog 2) (Protein MPP2) | UniProt NCBI |
| LPP | Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1089 | 1.16880143691e-05 | 0.25 | MPP6 LIN7A | VAM1-VELI1 complex |
| REAC:R-HSA-212676 | 0.00935228350379 | 0.25 | LIN7B LIN7A | Dopamine Neurotransmitter Release Cycle |
| REAC:R-HSA-9609736 | 0.0311651665682 | 0.25 | LIN7B LIN7A | Assembly and cell surface presentation of NMDA receptors |
| REAC:R-HSA-112310 | 0.0328409413955 | 0.25 | LIN7B LIN7A | Neurotransmitter release cycle |
| CORUM:3208 | 0.0497224828424 | 0.125 | LIN7A | LIN2-LIN7 complex |
| CORUM:6159 | 0.0497224828424 | 0.125 | LPP | LPP-PPP2CA-PPP2R3A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LIN7B | MPP2 | 0.963 | 0.871 | bioplex (MPP2) bioplex_WMM |
| LIN7A | MPP2 | 0.456 | 0.596 | bioplex (MPP2) bioplex_WMM |
| USP11 | CDA | 0.108 | 0.373 | fraction |
| CDA | MPP2 | 0.08 | 0.35 | bioplex (CDA) bioplex_WMM |
| CDA | LIN7A | 0.028 | 0.231 | bioplex (CDA) bioplex_WMM |
| LPP | CDA | 0.027 | 0.229 | fraction |
| USP11 | TCEAL4 | 0.025 | 0.212 | hein_WMM bioplex_WMM hein (USP11) |
| MPP6 | MPP2 | 0.024 | 0.213 | bioplex (MPP2) bioplex_WMM |
| MPP6 | LIN7A | 0.012 | 0.149 | bioplex_WMM WMM_only |
| CDA | MPP6 | 0.011 | 0.148 | bioplex (CDA) bioplex_WMM |
| LIN7B | MPP6 | 0.009 | 0.11 | bioplex_WMM WMM_only |
| LIN7B | LIN7A | 0.009 | 0.109 | bioplex_WMM WMM_only |
| USP11 | LPP | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| USP11 | LIN7A | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TCEAL4 | LIN7A | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TCEAL4 | MPP6 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| LPP | TCEAL4 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| TCEAL4 | MPP2 | 0.007 | 0.002 | bioplex (MPP2) |
| USP11 | MPP6 | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01555 has an average edge precision of 0.19 which is ranked 6309 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| LIN7B | HuMAP2_01171 HuMAP2_01555 HuMAP2_02238 HuMAP2_03001 |
| LIN7A | HuMAP2_01555 HuMAP2_02238 HuMAP2_03001 |
| TCEAL4 | HuMAP2_01555 HuMAP2_05656 |
| USP11 | HuMAP2_00350 HuMAP2_01555 HuMAP2_03852 HuMAP2_05656 HuMAP2_06382 |
| CDA | HuMAP2_01555 HuMAP2_03852 |
| MPP6 | HuMAP2_01555 HuMAP2_02238 HuMAP2_03001 |
| MPP2 | HuMAP2_01555 HuMAP2_02238 HuMAP2_03001 |
| LPP | HuMAP2_00636 HuMAP2_01555 HuMAP2_02719 HuMAP2_03271 HuMAP2_05765 HuMAP2_05803 |