hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01557
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CD274 | Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274) | UniProt NCBI |
| PDGFRB | Platelet-derived growth factor receptor beta (PDGF-R-beta) (PDGFR-beta) (EC 2.7.10.1) (Beta platelet-derived growth factor receptor) (Beta-type platelet-derived growth factor receptor) (CD140 antigen-like family member B) (Platelet-derived growth factor receptor 1) (PDGFR-1) (CD antigen CD140b) | UniProt NCBI |
| ATR | Serine/threonine-protein kinase ATR (EC 2.7.11.1) (Ataxia telangiectasia and Rad3-related protein) (FRAP-related protein 1) | UniProt NCBI |
| DEPDC1 | DEP domain-containing protein 1A | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:265 | 0.0499140284799 | 0.25 | ATR | ATR-ATRIP complex |
| CORUM:1133 | 0.0499140284799 | 0.25 | ATR | ATR-HDAC2 complex |
| CORUM:6413 | 0.0499140284799 | 0.25 | PDGFRB | PDGFB-PDGFRB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDGFRB | ATR | 0.113 | 0.381 | bioplex (PDGFRB) bioplex_WMM |
| CD274 | ATR | 0.083 | 0.35 | bioplex (CD274) bioplex_WMM |
| DEPDC1 | PDGFRB | 0.08 | 0.35 | bioplex (PDGFRB) bioplex_WMM |
| DEPDC1 | ATR | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01557 has an average edge precision of 0.271 which is ranked 5006 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CD274 | HuMAP2_01557 HuMAP2_01643 HuMAP2_02150 |
| PDGFRB | HuMAP2_01557 HuMAP2_01643 HuMAP2_01893 |
| ATR | HuMAP2_01557 HuMAP2_01643 HuMAP2_02150 |
| DEPDC1 | HuMAP2_00240 HuMAP2_00717 HuMAP2_01557 HuMAP2_01643 HuMAP2_01893 |