hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01574
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ITPA | Inosine triphosphate pyrophosphatase (ITPase) (Inosine triphosphatase) (EC 3.6.1.9) (Non-canonical purine NTP pyrophosphatase) (Non-standard purine NTP pyrophosphatase) (Nucleoside-triphosphate diphosphatase) (Nucleoside-triphosphate pyrophosphatase) (NTPase) (Putative oncogene protein hlc14-06-p) | UniProt NCBI |
| GSTO1 | Glutathione S-transferase omega-1 (GSTO-1) (EC 2.5.1.18) (Glutathione S-transferase omega 1-1) (GSTO 1-1) (Glutathione-dependent dehydroascorbate reductase) (EC 1.8.5.1) (Monomethylarsonic acid reductase) (MMA(V) reductase) (EC 1.20.4.2) (S-(Phenacyl)glutathione reductase) (SPG-R) | UniProt NCBI |
| LACTB2 | Endoribonuclease LACTB2 (EC 3.1.27.-) (Beta-lactamase-like protein 2) | UniProt NCBI |
| PARK7 | Protein/nucleic acid deglycase DJ-1 (EC 3.1.2.-) (EC 3.5.1.-) (EC 3.5.1.124) (Maillard deglycase) (Oncogene DJ1) (Parkinson disease protein 7) (Parkinsonism-associated deglycase) (Protein DJ-1) (DJ-1) | UniProt NCBI |
| NIT1 | Deaminated glutathione amidase (dGSH amidase) (EC 3.5.1.128) (Nitrilase homolog 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00983 | 0.0108715181024 | 0.4 | ITPA GSTO1 | Drug metabolism - other enzymes |
| CORUM:5830 | 0.0499494897235 | 0.2 | PARK7 | DJ-1-SNCA complex, high molecular weight complex |
| CORUM:5837 | 0.0499494897235 | 0.2 | PARK7 | PPD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LACTB2 | PARK7 | 0.973 | 0.886 | bioplex (LACTB2) bioplex_WMM fraction |
| ITPA | PARK7 | 0.936 | 0.85 | bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| PARK7 | GSTO1 | 0.934 | 0.85 | bioplex (GSTO1) bioplex_WMM Guru gupta_WMM fraction treiber_WMM |
| NIT1 | PARK7 | 0.901 | 0.825 | bioplex (NIT1) fraction treiber_WMM |
| ITPA | NIT1 | 0.269 | 0.483 | fraction |
| ITPA | GSTO1 | 0.058 | 0.325 | bioplex_WMM Guru fraction |
| NIT1 | GSTO1 | 0.011 | 0.138 | fraction treiber_WMM |
| LACTB2 | GSTO1 | 0.006 | 0.009 | bioplex_WMM fraction |
| ITPA | LACTB2 | 0.0 | 0.011 | bioplex_WMM fraction |
| LACTB2 | NIT1 | 0.0 | 0.008 | fraction |
Images
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Complex HuMAP2_01574 has an average edge precision of 0.439 which is ranked 2944 out of all 6965 complexes.
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