hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01577
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PTP4A2 | Protein tyrosine phosphatase type IVA 2 (EC 3.1.3.48) (HU-PP-1) (OV-1) (PTP(CAAXII)) (Protein-tyrosine phosphatase 4a2) (Protein-tyrosine phosphatase of regenerating liver 2) (PRL-2) | UniProt NCBI |
| PTP4A1 | Protein tyrosine phosphatase type IVA 1 (EC 3.1.3.48) (PTP(CAAXI)) (Protein-tyrosine phosphatase 4a1) (Protein-tyrosine phosphatase of regenerating liver 1) (PRL-1) | UniProt NCBI |
| CNNM4 | Metal transporter CNNM4 (Ancient conserved domain-containing protein 4) (Cyclin-M4) | UniProt NCBI |
| CNNM2 | Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2) | UniProt NCBI |
| PTP4A3 | Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3) | UniProt NCBI |
| KIF21B | Kinesin-like protein KIF21B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0004727 | 0.00676235117068 | 0.333333333333 | PTP4A3 PTP4A2 | prenylated protein tyrosine phosphatase activity |
| MIRNA:hsa-miR-3148 | 0.0192376991382 | 0.5 | PTP4A2 PTP4A1 CNNM4 | hsa-miR-3148 |
| MIRNA:hsa-miR-218-5p | 0.0294792252451 | 0.666666666667 | PTP4A2 KIF21B CNNM2 PTP4A1 | hsa-miR-218-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTP4A1 | PTP4A2 | 0.803 | 0.766 | hein_WMM bioplex (PTP4A2) bioplex_WMM |
| PTP4A3 | PTP4A2 | 0.443 | 0.586 | bioplex (PTP4A2) bioplex_WMM |
| PTP4A2 | CNNM4 | 0.056 | 0.313 | bioplex (PTP4A2) bioplex_WMM |
| CNNM2 | PTP4A2 | 0.024 | 0.21 | bioplex (PTP4A2) bioplex_WMM |
| PTP4A1 | KIF21B | 0.024 | 0.213 | hein_WMM hein (KIF21B) |
| KIF21B | PTP4A2 | 0.013 | 0.155 | hein_WMM hein (KIF21B) |
| PTP4A1 | PTP4A3 | 0.009 | 0.09 | bioplex_WMM WMM_only |
| PTP4A3 | CNNM4 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| PTP4A1 | CNNM4 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| CNNM2 | PTP4A1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| CNNM2 | PTP4A3 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| CNNM2 | CNNM4 | 0.007 | 0.007 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_01577 has an average edge precision of 0.198 which is ranked 6215 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PTP4A2 | HuMAP2_01577 HuMAP2_02976 HuMAP2_04301 HuMAP2_05281 HuMAP2_07000 |
| PTP4A1 | HuMAP2_01577 HuMAP2_02976 HuMAP2_05248 HuMAP2_05281 HuMAP2_07000 |
| CNNM4 | HuMAP2_01577 HuMAP2_04301 HuMAP2_05281 HuMAP2_07000 |
| CNNM2 | HuMAP2_01577 HuMAP2_04301 HuMAP2_05281 |
| PTP4A3 | HuMAP2_01577 HuMAP2_04301 HuMAP2_05281 HuMAP2_07000 |
| KIF21B | HuMAP2_01577 HuMAP2_02644 HuMAP2_04681 HuMAP2_05248 HuMAP2_05281 |