hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01580
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HK3 | Hexokinase-3 (EC 2.7.1.1) (Hexokinase type III) (HK III) | UniProt NCBI |
| HKDC1 | Putative hexokinase HKDC1 (EC 2.7.1.1) (Hexokinase domain-containing protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00524 | 1.45897544136e-06 | 1.0 | HK3 HKDC1 | Neomycin, kanamycin and gentamicin biosynthesis |
| KEGG:00052 | 5.12100379916e-05 | 1.0 | HK3 HKDC1 | Galactose metabolism |
| KEGG:00500 | 6.7842358023e-05 | 1.0 | HK3 HKDC1 | Starch and sucrose metabolism |
| KEGG:00051 | 7.70339033036e-05 | 1.0 | HK3 HKDC1 | Fructose and mannose metabolism |
| KEGG:04973 | 0.000113800084426 | 1.0 | HK3 HKDC1 | Carbohydrate digestion and absorption |
| KEGG:04930 | 0.000138019076752 | 1.0 | HK3 HKDC1 | Type II diabetes mellitus |
| KEGG:00520 | 0.00015100395818 | 1.0 | HK3 HKDC1 | Amino sugar and nucleotide sugar metabolism |
| WP:WP500 | 0.000261924676198 | 1.0 | HK3 HKDC1 | Glycogen Synthesis and Degradation |
| KEGG:00010 | 0.000284937903697 | 1.0 | HK3 HKDC1 | Glycolysis / Gluconeogenesis |
| KEGG:05230 | 0.000322579470084 | 1.0 | HK3 HKDC1 | Central carbon metabolism in cancer |
| KEGG:04066 | 0.000722192843471 | 1.0 | HK3 HKDC1 | HIF-1 signaling pathway |
| KEGG:01200 | 0.000939726081777 | 1.0 | HK3 HKDC1 | Carbon metabolism |
| KEGG:04910 | 0.00113070596705 | 1.0 | HK3 HKDC1 | Insulin signaling pathway |
| GO:0019158 | 0.00450823411379 | 1.0 | HK3 HKDC1 | mannokinase activity |
| GO:0008865 | 0.00450823411379 | 1.0 | HK3 HKDC1 | fructokinase activity |
| GO:0004396 | 0.00450823411379 | 1.0 | HK3 HKDC1 | hexokinase activity |
| GO:0004340 | 0.00450823411379 | 1.0 | HK3 HKDC1 | glucokinase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HK3 | HKDC1 | 0.798 | 0.764 | bioplex (HK3) bioplex_WMM |
Images
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Complex HuMAP2_01580 has an average edge precision of 0.764 which is ranked 1077 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HK3 | HuMAP2_01222 HuMAP2_01580 HuMAP2_01636 HuMAP2_02487 |
| HKDC1 | HuMAP2_01222 HuMAP2_01580 HuMAP2_01636 HuMAP2_02487 |