hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01606
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEC13 | Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) | UniProt NCBI |
| SESN2 | Sestrin-2 (EC 1.11.1.15) (Hypoxia-induced gene) | UniProt NCBI |
| WDR24 | GATOR complex protein WDR24 (WD repeat-containing protein 24) | UniProt NCBI |
| MIOS | GATOR complex protein MIOS (Missing oocyte meiosis regulator homolog) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6216 | 6.75163031135e-09 | 0.75 | MIOS SEC13 WDR24 | GATOR2 complex |
| GO:0061700 | 1.20758028692e-08 | 1.0 | SESN2 MIOS SEC13 WDR24 | GATOR2 complex |
| CORUM:6217 | 3.78034162849e-08 | 0.75 | MIOS SEC13 WDR24 | GATOR complex |
| CORUM:6753 | 3.78034162849e-08 | 0.75 | MIOS SEC13 WDR24 | SOG complex |
| GO:0035859 | 5.80614360177e-08 | 1.0 | SESN2 MIOS SEC13 WDR24 | Seh1-associated complex |
| KEGG:04150 | 3.10435795123e-07 | 1.0 | SESN2 MIOS SEC13 WDR24 | mTOR signaling pathway |
| GO:0032006 | 3.85835319231e-05 | 1.0 | SESN2 MIOS SEC13 WDR24 | regulation of TOR signaling |
| GO:0031929 | 7.12285743241e-05 | 1.0 | SESN2 MIOS SEC13 WDR24 | TOR signaling |
| GO:0032008 | 0.00217043933003 | 0.75 | MIOS SEC13 WDR24 | positive regulation of TOR signaling |
| GO:0034198 | 0.0025894674696 | 0.75 | SESN2 WDR24 MIOS | cellular response to amino acid starvation |
| GO:1990928 | 0.00281780772825 | 0.75 | SESN2 WDR24 MIOS | response to amino acid starvation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SEC13 | WDR24 | 0.925 | 0.843 | hein_WMM bioplex (SEC13) bioplex_WMM boldt boldt_WMM |
| MIOS | SEC13 | 0.816 | 0.773 | hein_WMM bioplex (SEC13) bioplex_WMM boldt boldt_WMM |
| WDR24 | SESN2 | 0.06 | 0.337 | hein_WMM bioplex_WMM hein (SESN2) |
| MIOS | SESN2 | 0.036 | 0.264 | hein_WMM bioplex_WMM hein (SESN2) |
| MIOS | WDR24 | 0.014 | 0.141 | hein_WMM bioplex_WMM boldt boldt_WMM |
| SEC13 | SESN2 | 0.013 | 0.149 | hein_WMM bioplex (SEC13) bioplex_WMM hein (SESN2) |
Images
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Complex HuMAP2_01606 has an average edge precision of 0.418 which is ranked 3129 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEC13 | HuMAP2_00541 HuMAP2_01606 HuMAP2_03792 HuMAP2_05315 HuMAP2_06753 |
| SESN2 | HuMAP2_00541 HuMAP2_01606 HuMAP2_02429 HuMAP2_06823 |
| WDR24 | HuMAP2_00541 HuMAP2_01606 HuMAP2_03326 HuMAP2_03792 HuMAP2_06753 HuMAP2_06823 |
| MIOS | HuMAP2_00541 HuMAP2_01606 HuMAP2_03326 HuMAP2_03792 HuMAP2_06753 |