hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01610
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ESS2 | Splicing factor ESS-2 homolog (DiGeorge syndrome critical region 13) (DiGeorge syndrome critical region 14) (DiGeorge syndrome protein H) (DGS-H) (Protein ES2) | UniProt NCBI |
| CRNKL1 | Crooked neck-like protein 1 (Crooked neck homolog) (hCrn) | UniProt NCBI |
| CWC15 | Spliceosome-associated protein CWC15 homolog | UniProt NCBI |
| SNW1 | SNW domain-containing protein 1 (Nuclear protein SkiP) (Nuclear receptor coactivator NCoA-62) (Ski-interacting protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1181 | 6.46811126422e-08 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | C complex spliceosome |
| CORUM:351 | 6.95120006013e-07 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | Spliceosome |
| GO:0071013 | 4.48297714516e-05 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | catalytic step 2 spliceosome |
| KEGG:03040 | 9.56545898299e-05 | 0.75 | CRNKL1 SNW1 CWC15 | Spliceosome |
| GO:0005681 | 0.000657808747052 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | spliceosomal complex |
| REAC:R-HSA-72163 | 0.0012370641562 | 0.75 | CRNKL1 SNW1 CWC15 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.00141192686346 | 0.75 | CRNKL1 SNW1 CWC15 | mRNA Splicing |
| GO:0071007 | 0.00147288799354 | 0.75 | CRNKL1 SNW1 CWC15 | U2-type catalytic step 2 spliceosome |
| REAC:R-HSA-72203 | 0.00285014014969 | 0.75 | CRNKL1 SNW1 CWC15 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0000377 | 0.00944788787297 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile |
| GO:0000398 | 0.00944788787297 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | mRNA splicing, via spliceosome |
| GO:0000375 | 0.00981835447646 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | RNA splicing, via transesterification reactions |
| GO:0008380 | 0.0187431053955 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | RNA splicing |
| GO:0006397 | 0.0251226492241 | 1.0 | CRNKL1 SNW1 CWC15 ESS2 | mRNA processing |
| GO:0005684 | 0.0439367749778 | 0.75 | CRNKL1 SNW1 CWC15 | U2-type spliceosomal complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SNW1 | CRNKL1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru youn_WMM hein (SNW1) gupta_WMM fraction treiber_WMM |
| SNW1 | CWC15 | 0.946 | 0.857 | hein_WMM bioplex_WMM youn_WMM hein (SNW1) gupta_WMM |
| CRNKL1 | CWC15 | 0.887 | 0.818 | hein_WMM bioplex_WMM youn_WMM hein (CRNKL1) gupta_WMM |
| SNW1 | ESS2 | 0.775 | 0.752 | hein_WMM bioplex_WMM boldt youn_WMM hein (SNW1) gupta_WMM boldt_WMM |
| CRNKL1 | ESS2 | 0.015 | 0.141 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| CWC15 | ESS2 | 0.009 | 0.103 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_01610 has an average edge precision of 0.603 which is ranked 1927 out of all 6965 complexes.
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