hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01611
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYTL2 | Synaptotagmin-like protein 2 (Breast cancer-associated antigen SGA-72M) (Exophilin-4) | UniProt NCBI |
| SYTL1 | Synaptotagmin-like protein 1 (Exophilin-7) (Protein JFC1) | UniProt NCBI |
| RPH3AL | Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein) | UniProt NCBI |
| SYTL5 | Synaptotagmin-like protein 5 | UniProt NCBI |
| SYTL3 | Synaptotagmin-like protein 3 (Exophilin-6) | UniProt NCBI |
| RAB27B | Ras-related protein Rab-27B (C25KG) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2291 | 1.36549638399e-17 | 1.0 | SYTL1 RAB27B SYTL5 SYTL3 RPH3AL SYTL2 | Deregulation of Rab and Rab Effector Genes in Bladder Cancer |
| GO:0030133 | 0.000315161281723 | 0.833333333333 | RAB27B SYTL1 SYTL3 SYTL2 SYTL5 | transport vesicle |
| GO:0042470 | 0.00278918949629 | 0.5 | SYTL1 SYTL2 RAB27B | melanosome |
| GO:0048770 | 0.00278918949629 | 0.5 | SYTL1 SYTL2 RAB27B | pigment granule |
| GO:0070382 | 0.00338879477277 | 0.666666666667 | SYTL1 SYTL3 SYTL2 SYTL5 | exocytic vesicle |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB27B | SYTL2 | 1.0 | 0.949 | bioplex (RAB27B) bioplex_WMM |
| SYTL1 | RAB27B | 0.999 | 0.949 | bioplex (RAB27B) bioplex_WMM |
| SYTL5 | RAB27B | 0.998 | 0.939 | bioplex (RAB27B) bioplex_WMM |
| RAB27B | RPH3AL | 0.419 | 0.573 | bioplex (RAB27B) bioplex_WMM |
| RAB27B | SYTL3 | 0.173 | 0.433 | bioplex (RAB27B) bioplex_WMM |
| SYTL2 | RPH3AL | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL1 | SYTL3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL2 | SYTL3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL1 | SYTL2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL5 | SYTL1 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL5 | SYTL2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL5 | RPH3AL | 0.009 | 0.095 | bioplex_WMM WMM_only |
| RPH3AL | SYTL3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL1 | RPH3AL | 0.009 | 0.095 | bioplex_WMM WMM_only |
| SYTL5 | SYTL3 | 0.009 | 0.095 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01611 has an average edge precision of 0.32 which is ranked 4350 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SYTL2 | HuMAP2_01047 HuMAP2_01611 |
| SYTL1 | HuMAP2_01047 HuMAP2_01611 |
| RPH3AL | HuMAP2_01611 |
| SYTL5 | HuMAP2_01047 HuMAP2_01611 |
| SYTL3 | HuMAP2_01611 |
| RAB27B | HuMAP2_01047 HuMAP2_01611 |