hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01621
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| KDM4A | Lysine-specific demethylase 4A (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3A) (Jumonji domain-containing protein 2A) | UniProt NCBI |
| CCL22 | C-C motif chemokine 22 (CC chemokine STCP-1) (MDC(1-69)) (Macrophage-derived chemokine) (Small-inducible cytokine A22) (Stimulated T-cell chemotactic protein 1) [Cleaved into: MDC(3-69); MDC(5-69); MDC(7-69)] | UniProt NCBI |
| KDM4B | Lysine-specific demethylase 4B (EC 1.14.11.-) (JmjC domain-containing histone demethylation protein 3B) (Jumonji domain-containing protein 2B) | UniProt NCBI |
| CHORDC1 | Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana) | UniProt NCBI |
| SEPHS2 | Selenide, water dikinase 2 (EC 2.7.9.3) (Selenium donor protein 2) (Selenophosphate synthase 2) | UniProt NCBI |
| PCYT2 | Ethanolamine-phosphate cytidylyltransferase (EC 2.7.7.14) (CTP:phosphoethanolamine cytidylyltransferase) (Phosphorylethanolamine transferase) | UniProt NCBI |
| UROS | Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3214842 | 0.036845984894 | 0.285714285714 | KDM4A KDM4B | HDMs demethylate histones |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KDM4A | CCL22 | 0.397 | 0.558 | bioplex (CCL22) bioplex_WMM |
| KDM4A | KDM4B | 0.34 | 0.528 | bioplex (KDM4B) bioplex_WMM |
| KDM4B | CHORDC1 | 0.162 | 0.419 | hein_WMM hein (CHORDC1) |
| CHORDC1 | PCYT2 | 0.069 | 0.348 | fraction |
| SEPHS2 | CCL22 | 0.036 | 0.266 | bioplex (CCL22) bioplex_WMM |
| UROS | SEPHS2 | 0.025 | 0.211 | bioplex (UROS) bioplex_WMM |
| SEPHS2 | KDM4A | 0.008 | 0.013 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01621 has an average edge precision of 0.335 which is ranked 4180 out of all 6965 complexes.
Related Complexes