hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01656
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DEFA1 | Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)] | UniProt NCBI |
| DEFA1 | Neutrophil defensin 1 (Defensin, alpha 1) (HNP-1) (HP-1) (HP1) [Cleaved into: HP 1-56; Neutrophil defensin 2 (HNP-2) (HP-2) (HP2)] | UniProt NCBI |
| IGFBP2 | Insulin-like growth factor-binding protein 2 (IBP-2) (IGF-binding protein 2) (IGFBP-2) | UniProt NCBI |
| BMPER | BMP-binding endothelial regulator protein (Bone morphogenetic protein-binding endothelial cell precursor-derived regulator) (Protein crossveinless-2) (hCV2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0006615 | 0.0497341708567 | 0.5 | BMPER | Absent in utero rib ossification |
| HP:0008435 | 0.0497341708567 | 0.5 | BMPER | Absent in utero ossification of vertebral bodies |
| HP:0025370 | 0.0497341708567 | 0.5 | BMPER | Abnormal ossification of the sacrum |
| HP:0030290 | 0.0497341708567 | 0.5 | BMPER | Unossified sacrum |
| HP:0100752 | 0.0497341708567 | 0.5 | BMPER | Abnormal liver lobulation |
| CORUM:6191 | 0.0499173803268 | 0.5 | IGFBP2 | IGF2-IGFBP2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DEFA1 | DEFA1 | 0.991 | 0.909 | bioplex (DEFA1) |
| DEFA1 | IGFBP2 | 0.229 | 0.468 | bioplex (DEFA1) |
| DEFA1 | BMPER | 0.178 | 0.438 | bioplex (DEFA1) |
| IGFBP2 | DEFA1 | 0.008 | 0.096 | bioplex_WMM WMM_only |
| BMPER | DEFA1 | 0.008 | 0.096 | bioplex_WMM WMM_only |
| IGFBP2 | BMPER | 0.008 | 0.085 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01656 has an average edge precision of 0.349 which is ranked 3990 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DEFA1 | HuMAP2_01656 HuMAP2_02212 HuMAP2_05020 |
| DEFA1 | HuMAP2_01656 HuMAP2_02212 HuMAP2_05020 |
| IGFBP2 | HuMAP2_01656 HuMAP2_05020 |
| BMPER | HuMAP2_01656 HuMAP2_05020 HuMAP2_05505 |