hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01660
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TJP2 | Tight junction protein ZO-2 (Tight junction protein 2) (Zona occludens protein 2) (Zonula occludens protein 2) | UniProt NCBI |
| TJP1 | Tight junction protein ZO-1 (Tight junction protein 1) (Zona occludens protein 1) (Zonula occludens protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-351906 | 9.21757904306e-05 | 1.0 | TJP1 TJP2 | Apoptotic cleavage of cell adhesion proteins |
| KEGG:05110 | 0.000164572429785 | 1.0 | TJP1 TJP2 | Vibrio cholerae infection |
| REAC:R-HSA-2028269 | 0.000286582912066 | 1.0 | TJP1 TJP2 | Signaling by Hippo |
| REAC:R-HSA-111465 | 0.00111616502594 | 1.0 | TJP1 TJP2 | Apoptotic cleavage of cellular proteins |
| KEGG:04530 | 0.00152317036077 | 1.0 | TJP1 TJP2 | Tight junction |
| REAC:R-HSA-75153 | 0.00213680241453 | 1.0 | TJP1 TJP2 | Apoptotic execution phase |
| GO:0090557 | 0.00676235117068 | 1.0 | TJP1 TJP2 | establishment of endothelial intestinal barrier |
| REAC:R-HSA-109581 | 0.0237914094719 | 1.0 | TJP1 TJP2 | Apoptosis |
| REAC:R-HSA-5357801 | 0.0246461304377 | 1.0 | TJP1 TJP2 | Programmed Cell Death |
| REAC:R-HSA-191650 | 0.0499173803268 | 0.5 | TJP1 | Regulation of gap junction activity |
| CORUM:6351 | 0.0499173803268 | 0.5 | TJP1 | PKP1-ZO-1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TJP1 | TJP2 | 0.999 | 0.949 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
Click to enlarge
Complex HuMAP2_01660 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TJP2 | HuMAP2_01660 HuMAP2_06792 |
| TJP1 | HuMAP2_01660 HuMAP2_06459 HuMAP2_06792 |