hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01661
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MICAL3 | [F-actin]-monooxygenase MICAL3 (EC 1.14.13.225) (Molecule interacting with CasL protein 3) (MICAL-3) | UniProt NCBI |
| MICALL1 | MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13) | UniProt NCBI |
| RAB8A | Ras-related protein Rab-8A (Oncogene c-mel) | UniProt NCBI |
| MICALL2 | MICAL-like protein 2 (Junctional Rab13-binding protein) (Molecule interacting with CasL-like 2) (MICAL-L2) | UniProt NCBI |
| RAB8B | Ras-related protein Rab-8B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04530 | 0.000424294655338 | 0.6 | MICALL2 RAB8B RAB8A | Tight junction |
| GO:0055037 | 0.000962610785502 | 0.8 | MICALL2 RAB8A MICALL1 RAB8B | recycling endosome |
| GO:0031941 | 0.00541762673764 | 0.6 | MICAL3 MICALL1 MICALL2 | filamentous actin |
| REAC:R-HSA-8854214 | 0.012121451174 | 0.4 | RAB8B RAB8A | TBC/RABGAPs |
| GO:0055038 | 0.0166549756635 | 0.6 | RAB8A MICALL1 RAB8B | recycling endosome membrane |
| REAC:R-HSA-8873719 | 0.0253191001807 | 0.4 | RAB8B RAB8A | RAB geranylgeranylation |
| GO:0048210 | 0.0450641792523 | 0.4 | RAB8B RAB8A | Golgi vesicle fusion to target membrane |
| REAC:R-HSA-8876198 | 0.0476518941102 | 0.4 | RAB8B RAB8A | RAB GEFs exchange GTP for GDP on RABs |
| CORUM:7333 | 0.0499494897235 | 0.2 | MICALL1 | MICALL1-RAB13 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB8B | RAB8A | 0.89 | 0.818 | bioplex (RAB8B) bioplex_WMM gupta_WMM |
| RAB8B | MICALL2 | 0.639 | 0.686 | bioplex (RAB8B) bioplex_WMM |
| MICALL1 | RAB8B | 0.188 | 0.439 | bioplex (RAB8B) bioplex_WMM |
| RAB8B | MICAL3 | 0.072 | 0.353 | bioplex (RAB8B) bioplex_WMM |
| MICALL1 | RAB8A | 0.009 | 0.089 | bioplex_WMM boldt (RAB8A) gupta_WMM boldt_WMM |
| MICALL1 | MICALL2 | 0.008 | 0.093 | bioplex_WMM WMM_only |
| RAB8A | MICALL2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| MICAL3 | MICALL2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| RAB8A | MICAL3 | 0.008 | 0.065 | bioplex_WMM boldt (RAB8A) gupta_WMM boldt_WMM |
| MICALL1 | MICAL3 | 0.008 | 0.041 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_01661 has an average edge precision of 0.276 which is ranked 4944 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MICAL3 | HuMAP2_01626 HuMAP2_01661 |
| MICALL1 | HuMAP2_00974 HuMAP2_01102 HuMAP2_01103 HuMAP2_01661 HuMAP2_02945 HuMAP2_04010 HuMAP2_06001 HuMAP2_06285 HuMAP2_06775 |
| RAB8A | HuMAP2_01064 HuMAP2_01661 HuMAP2_06144 HuMAP2_06285 |
| MICALL2 | HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |
| RAB8B | HuMAP2_01064 HuMAP2_01661 HuMAP2_06001 HuMAP2_06144 HuMAP2_06285 |