hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01667
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACGAP1 | Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | UniProt NCBI |
| SMNDC1 | Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1) | UniProt NCBI |
| KIF23 | Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | UniProt NCBI |
| SECISBP2L | Selenocysteine insertion sequence-binding protein 2-like (SECIS-binding protein 2-like) | UniProt NCBI |
| XRCC5 | X-ray repair cross-complementing protein 5 (EC 3.6.4.-) (86 kDa subunit of Ku antigen) (ATP-dependent DNA helicase 2 subunit 2) (ATP-dependent DNA helicase II 80 kDa subunit) (CTC box-binding factor 85 kDa subunit) (CTC85) (CTCBF) (DNA repair protein XRCC5) (Ku80) (Ku86) (Lupus Ku autoantigen protein p86) (Nuclear factor IV) (Thyroid-lupus autoantigen) (TLAA) (X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)) | UniProt NCBI |
| PSG9 | Pregnancy-specific beta-1-glycoprotein 9 (PS-beta-G-9) (PSBG-9) (Pregnancy-specific glycoprotein 9) (PS34) (Pregnancy-specific beta-1 glycoprotein B) (PS-beta-B) (Pregnancy-specific beta-1-glycoprotein 11) (PS-beta-G-11) (PSBG-11) (Pregnancy-specific glycoprotein 11) (Pregnancy-specific glycoprotein 7) (PSG7) | UniProt NCBI |
| SHCBP1 | SHC SH2 domain-binding protein 1 | UniProt NCBI |
| PSG3 | Pregnancy-specific beta-1-glycoprotein 3 (PS-beta-G-3) (PSBG-3) (Pregnancy-specific glycoprotein 3) (Carcinoembryonic antigen SG5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7440 | 1.16880143691e-05 | 0.25 | KIF23 RACGAP1 | KIF23-RACGAP1 complex |
| CORUM:7439 | 3.50546248845e-05 | 0.25 | KIF23 RACGAP1 | ECT2-KIF23-RACGAP1 complex |
| CORUM:929 | 3.62776142917e-05 | 0.375 | SHCBP1 RACGAP1 KIF23 | CEN complex |
| REAC:R-HSA-109582 | 0.0183420803349 | 0.5 | PSG3 KIF23 RACGAP1 PSG9 | Hemostasis |
| GO:0097149 | 0.0378589948753 | 0.25 | KIF23 RACGAP1 | centralspindlin complex |
| CORUM:328 | 0.0497224828424 | 0.125 | XRCC5 | Ku antigen complex |
| CORUM:4081 | 0.0497224828424 | 0.125 | XRCC5 | Ku antigen complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RACGAP1 | KIF23 | 1.0 | 0.949 | hein_WMM bioplex (RACGAP1) bioplex_WMM Guru youn_WMM hein (KIF23,RACGAP1) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| PSG9 | SHCBP1 | 0.99 | 0.909 | bioplex (PSG9) bioplex_WMM |
| SHCBP1 | RACGAP1 | 0.957 | 0.863 | hein_WMM bioplex (RACGAP1) bioplex_WMM youn_WMM hein (RACGAP1,SHCBP1) boldt_WMM |
| PSG9 | SECISBP2L | 0.257 | 0.48 | bioplex (PSG9) bioplex_WMM |
| PSG9 | PSG3 | 0.212 | 0.462 | bioplex (PSG3) bioplex_WMM |
| XRCC5 | SMNDC1 | 0.14 | 0.407 | bioplex_WMM youn_WMM gupta_WMM fraction |
| KIF23 | SMNDC1 | 0.11 | 0.379 | youn_WMM gupta_WMM fraction |
| SHCBP1 | KIF23 | 0.061 | 0.334 | hein_WMM bioplex_WMM youn_WMM hein (KIF23,SHCBP1) gupta_WMM boldt_WMM |
| RACGAP1 | SMNDC1 | 0.042 | 0.27 | hein_WMM youn_WMM gupta_WMM fraction |
| SHCBP1 | SECISBP2L | 0.008 | 0.086 | bioplex_WMM youn_WMM WMM_only |
| KIF23 | XRCC5 | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only treiber_WMM |
| XRCC5 | SECISBP2L | 0.007 | 0.002 | youn_WMM WMM_only |
| SMNDC1 | SECISBP2L | 0.007 | 0.001 | youn_WMM WMM_only |
| RACGAP1 | SECISBP2L | 0.007 | 0.001 | youn_WMM WMM_only |
| SHCBP1 | XRCC5 | 0.007 | 0.0 | youn_WMM gupta_WMM WMM_only |
| KIF23 | SECISBP2L | 0.007 | 0.002 | youn_WMM WMM_only |
| RACGAP1 | XRCC5 | 0.006 | 0.003 | bioplex (RACGAP1) youn_WMM gupta_WMM treiber_WMM |
Images
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Complex HuMAP2_01667 has an average edge precision of 0.303 which is ranked 4539 out of all 6965 complexes.
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