hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01699
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DHRS7 | Dehydrogenase/reductase SDR family member 7 (EC 1.1.-.-) (Retinal short-chain dehydrogenase/reductase 4) (retSDR4) (Short chain dehydrogenase/reductase family 34C member 1) | UniProt NCBI |
| THEM6 | Protein THEM6 (Mesenchymal stem cell protein DSCD75) (Thioesterase superfamily member 6) | UniProt NCBI |
| SRPRB | Signal recognition particle receptor subunit beta (SR-beta) (Protein APMCF1) | UniProt NCBI |
| SRPRA | Signal recognition particle receptor subunit alpha (SR-alpha) (Docking protein alpha) (DP-alpha) | UniProt NCBI |
| COX5A | Cytochrome c oxidase subunit 5A, mitochondrial (Cytochrome c oxidase polypeptide Va) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03060 | 0.0010832092153 | 0.4 | SRPRB SRPRA | Protein export |
| REAC:R-HSA-381038 | 0.0126969553517 | 0.4 | SRPRB SRPRA | XBP1(S) activates chaperone genes |
| REAC:R-HSA-381070 | 0.0138877528683 | 0.4 | SRPRB SRPRA | IRE1alpha activates chaperones |
| REAC:R-HSA-381119 | 0.0454350363854 | 0.4 | SRPRB SRPRA | Unfolded Protein Response (UPR) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SRPRB | SRPRA | 1.0 | 0.949 | hein_WMM bioplex (SRPRA,SRPRB) bioplex_WMM Guru boldt youn_WMM hein (SRPRA) gupta_WMM fraction boldt_WMM |
| DHRS7 | SRPRB | 0.066 | 0.348 | bioplex (SRPRB) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| THEM6 | SRPRB | 0.058 | 0.326 | bioplex (SRPRB) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SRPRA | COX5A | 0.041 | 0.269 | bioplex (SRPRA) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| DHRS7 | THEM6 | 0.01 | 0.126 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DHRS7 | SRPRA | 0.01 | 0.121 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| THEM6 | COX5A | 0.007 | 0.003 | bioplex_WMM boldt boldt_WMM |
| DHRS7 | COX5A | 0.007 | 0.0 | bioplex_WMM WMM_only |
| THEM6 | SRPRA | 0.007 | 0.006 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SRPRB | COX5A | 0.007 | 0.003 | bioplex (SRPRB) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
Images
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Complex HuMAP2_01699 has an average edge precision of 0.215 which is ranked 5942 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DHRS7 | HuMAP2_00287 HuMAP2_01487 HuMAP2_01699 HuMAP2_06362 |
| THEM6 | HuMAP2_01699 HuMAP2_02446 |
| SRPRB | HuMAP2_01699 HuMAP2_02446 HuMAP2_05917 |
| SRPRA | HuMAP2_01699 HuMAP2_02248 HuMAP2_02446 HuMAP2_05917 HuMAP2_06129 |
| COX5A | HuMAP2_01699 HuMAP2_02248 HuMAP2_06129 |