hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01703
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DST | Dystonin (230 kDa bullous pemphigoid antigen) (230/240 kDa bullous pemphigoid antigen) (Bullous pemphigoid antigen 1) (BPA) (Bullous pemphigoid antigen) (Dystonia musculorum protein) (Hemidesmosomal plaque protein) | UniProt NCBI |
| WDR45B | WD repeat domain phosphoinositide-interacting protein 3 (WIPI-3) (WD repeat-containing protein 45-like) (WDR45-like protein) (WD repeat-containing protein 45B) (WIPI49-like protein) | UniProt NCBI |
| FAM114A1 | Protein NOXP20 (Nervous system overexpressed protein 20) (Protein FAM114A1) | UniProt NCBI |
| GAS2L1 | GAS2-like protein 1 (GAS2-related protein on chromosome 22) (Growth arrest-specific protein 2-like 1) | UniProt NCBI |
| MAPRE1 | Microtubule-associated protein RP/EB family member 1 (APC-binding protein EB1) (End-binding protein 1) (EB1) | UniProt NCBI |
| MAPRE3 | Microtubule-associated protein RP/EB family member 3 (EB1 protein family member 3) (EBF3) (End-binding protein 3) (EB3) (RP3) | UniProt NCBI |
| KIF18B | Kinesin-like protein KIF18B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035371 | 1.99723678299e-09 | 0.714285714286 | KIF18B GAS2L1 MAPRE1 MAPRE3 DST | microtubule plus-end |
| GO:1990752 | 1.68636544732e-08 | 0.714285714286 | KIF18B GAS2L1 MAPRE1 MAPRE3 DST | microtubule end |
| GO:1904825 | 1.27120391093e-05 | 0.428571428571 | GAS2L1 MAPRE1 MAPRE3 | protein localization to microtubule plus-end |
| GO:1905725 | 1.27120391093e-05 | 0.428571428571 | GAS2L1 MAPRE1 MAPRE3 | protein localization to microtubule end |
| GO:0061673 | 6.35345863999e-05 | 0.428571428571 | MAPRE1 KIF18B MAPRE3 | mitotic spindle astral microtubule |
| GO:0000235 | 0.000266683990267 | 0.428571428571 | MAPRE1 KIF18B MAPRE3 | astral microtubule |
| GO:0005818 | 0.000266683990267 | 0.428571428571 | MAPRE1 KIF18B MAPRE3 | aster |
| GO:0005874 | 0.000899327340958 | 0.714285714286 | KIF18B GAS2L1 MAPRE1 MAPRE3 DST | microtubule |
| GO:0035372 | 0.000907263777246 | 0.428571428571 | GAS2L1 MAPRE1 MAPRE3 | protein localization to microtubule |
| GO:0051010 | 0.00144279242783 | 0.428571428571 | MAPRE1 MAPRE3 DST | microtubule plus-end binding |
| GO:0031109 | 0.0027945908108 | 0.571428571429 | GAS2L1 MAPRE1 KIF18B MAPRE3 | microtubule polymerization or depolymerization |
| GO:0099513 | 0.0111714152933 | 0.714285714286 | KIF18B GAS2L1 MAPRE1 MAPRE3 DST | polymeric cytoskeletal fiber |
| GO:0051233 | 0.0142076090165 | 0.428571428571 | MAPRE1 KIF18B MAPRE3 | spindle midzone |
| GO:0000226 | 0.0271422741221 | 0.714285714286 | KIF18B GAS2L1 MAPRE1 MAPRE3 DST | microtubule cytoskeleton organization |
| GO:1905721 | 0.0283955176165 | 0.285714285714 | MAPRE1 MAPRE3 | mitotic spindle astral microtubule end |
| GO:0072698 | 0.0389125948999 | 0.428571428571 | GAS2L1 MAPRE1 MAPRE3 | protein localization to microtubule cytoskeleton |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DST | MAPRE1 | 1.0 | 0.949 | hein_WMM bioplex (MAPRE1) bioplex_WMM youn_WMM hein (MAPRE1) gupta_WMM boldt_WMM |
| MAPRE1 | MAPRE3 | 1.0 | 0.949 | bioplex (MAPRE1) bioplex_WMM boldt (MAPRE1) gupta_WMM boldt_WMM |
| MAPRE3 | GAS2L1 | 1.0 | 0.949 | bioplex (GAS2L1) bioplex_WMM |
| MAPRE1 | GAS2L1 | 0.991 | 0.909 | hein_WMM bioplex (GAS2L1) bioplex_WMM hein (MAPRE1) |
| MAPRE1 | KIF18B | 0.826 | 0.774 | hein_WMM bioplex (MAPRE1) bioplex_WMM boldt (MAPRE1) youn_WMM hein (MAPRE1) boldt_WMM |
| WDR45B | GAS2L1 | 0.047 | 0.293 | bioplex (GAS2L1) bioplex_WMM |
| FAM114A1 | MAPRE3 | 0.029 | 0.233 | fraction |
| MAPRE1 | FAM114A1 | 0.028 | 0.231 | fraction |
| DST | MAPRE3 | 0.008 | 0.085 | bioplex_WMM gupta_WMM WMM_only boldt_WMM |
| DST | KIF18B | 0.008 | 0.016 | hein_WMM bioplex_WMM youn_WMM WMM_only boldt_WMM |
| KIF18B | MAPRE3 | 0.007 | 0.006 | bioplex_WMM boldt boldt_WMM |
| KIF18B | GAS2L1 | 0.007 | 0.003 | hein_WMM WMM_only |
| WDR45B | MAPRE3 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| KIF18B | WDR45B | 0.007 | 0.005 | bioplex_WMM WMM_only |
| MAPRE1 | WDR45B | 0.007 | 0.006 | bioplex_WMM WMM_only |
| DST | GAS2L1 | 0.006 | 0.005 | hein_WMM WMM_only |
Images
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Complex HuMAP2_01703 has an average edge precision of 0.338 which is ranked 4142 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DST | HuMAP2_01478 HuMAP2_01703 HuMAP2_02770 HuMAP2_03129 |
| WDR45B | HuMAP2_01703 HuMAP2_01816 HuMAP2_02228 HuMAP2_03854 HuMAP2_04879 HuMAP2_06295 |
| FAM114A1 | HuMAP2_01703 HuMAP2_02228 HuMAP2_03854 |
| GAS2L1 | HuMAP2_01703 HuMAP2_01816 HuMAP2_02228 HuMAP2_03854 HuMAP2_06295 |
| MAPRE1 | HuMAP2_01478 HuMAP2_01703 HuMAP2_03129 |
| MAPRE3 | HuMAP2_01703 HuMAP2_02228 HuMAP2_03854 HuMAP2_06295 |
| KIF18B | HuMAP2_01478 HuMAP2_01703 HuMAP2_02602 HuMAP2_04670 |