hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01708
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DYNC2H1 | Cytoplasmic dynein 2 heavy chain 1 (Cytoplasmic dynein 2 heavy chain) (Dynein cytoplasmic heavy chain 2) (Dynein heavy chain 11) (hDHC11) (Dynein heavy chain isotype 1B) | UniProt NCBI |
| DYNC2LI1 | Cytoplasmic dynein 2 light intermediate chain 1 (Dynein 2 light intermediate chain) | UniProt NCBI |
| PCYOX1 | Prenylcysteine oxidase 1 (EC 1.8.3.5) (Prenylcysteine lyase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6236 | 0.00022139720913 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Dynein-2 complex, cytoplasmic |
| WP:WP4532 | 0.000336301959938 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Intraflagellar transport proteins binding to dynein |
| KEGG:04962 | 0.000348719274028 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Vasopressin-regulated water reabsorption |
| HP:0000888 | 0.000803978270478 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Horizontal ribs |
| WP:WP4536 | 0.00501588895599 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Genes related to primary cilium development (based on CRISPR) |
| HP:0000090 | 0.00556051868131 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Nephronophthisis |
| HP:0010306 | 0.00759733122278 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Short thorax |
| HP:0100957 | 0.00834660940556 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Abnormal renal medulla morphology |
| REAC:R-HSA-5620924 | 0.00851790571699 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Intraflagellar transport |
| HP:0001830 | 0.00873443203011 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Postaxial foot polydactyly |
| HP:0000773 | 0.0121532611158 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Short ribs |
| HP:0010579 | 0.0161338784795 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Cone-shaped epiphysis |
| HP:0010322 | 0.0172167410086 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Abnormality of the 5th toe |
| HP:0000142 | 0.023156827915 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Abnormal vagina morphology |
| HP:0008873 | 0.029972334664 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Disproportionate short-limb short stature |
| HP:0006712 | 0.0314403819239 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Aplasia/Hypoplasia of the ribs |
| HP:0001162 | 0.0329433889933 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Postaxial hand polydactyly |
| HP:0000112 | 0.0329433889933 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Nephropathy |
| HP:0002983 | 0.0384790851177 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Micromelia |
| HP:0000889 | 0.0393048254184 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Abnormality of the clavicle |
| HP:0000774 | 0.0401392937999 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Narrow chest |
| HP:0001773 | 0.0409824890748 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Short foot |
| HP:0001829 | 0.0409824890748 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Foot polydactyly |
| HP:0009136 | 0.044442515366 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Duplication involving bones of the feet |
| HP:0003498 | 0.0453293273008 | 0.666666666667 | DYNC2LI1 DYNC2H1 | Disproportionate short stature |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DYNC2LI1 | DYNC2H1 | 0.988 | 0.901 | hein_WMM bioplex (DYNC2LI1) bioplex_WMM boldt (DYNC2LI1) boldt_WMM |
| PCYOX1 | DYNC2LI1 | 0.026 | 0.221 | bioplex (DYNC2LI1) bioplex_WMM boldt (DYNC2LI1) boldt_WMM |
| PCYOX1 | DYNC2H1 | 0.007 | 0.008 | bioplex_WMM boldt boldt_WMM |
Images
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Complex HuMAP2_01708 has an average edge precision of 0.377 which is ranked 3564 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DYNC2H1 | HuMAP2_01708 HuMAP2_02390 |
| DYNC2LI1 | HuMAP2_01708 HuMAP2_02390 |
| PCYOX1 | HuMAP2_01002 HuMAP2_01708 HuMAP2_03760 HuMAP2_04162 HuMAP2_06005 |