hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01711
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MINDY3 | Ubiquitin carboxyl-terminal hydrolase MINDY-3 (EC 3.4.19.12) (Dermal papilla-derived protein 5) (Deubiquitinating enzyme MINDY-3) (Protein CARP) | UniProt NCBI |
| EPN2 | Epsin-2 (EPS-15-interacting protein 2) | UniProt NCBI |
| UBB | Polyubiquitin-B [Cleaved into: Ubiquitin] | UniProt NCBI |
| EPN3 | Epsin-3 (EPS-15-interacting protein 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.000539397470166 | 0.75 | EPN3 UBB EPN2 | Endocytosis |
| REAC:R-HSA-8856825 | 0.0390714342086 | 0.5 | EPN2 UBB | Cargo recognition for clathrin-mediated endocytosis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EPN2 | EPN3 | 1.0 | 0.949 | bioplex (EPN3) bioplex_WMM youn_WMM |
| EPN3 | UBB | 0.5 | 0.621 | bioplex (EPN3) bioplex_WMM gupta_WMM |
| UBB | MINDY3 | 0.076 | 0.358 | bioplex (MINDY3) bioplex_WMM |
| EPN2 | UBB | 0.007 | 0.01 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_01711 has an average edge precision of 0.484 which is ranked 2596 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MINDY3 | HuMAP2_01711 |
| EPN2 | HuMAP2_00145 HuMAP2_01711 HuMAP2_04391 HuMAP2_05841 HuMAP2_05939 HuMAP2_06942 |
| UBB | HuMAP2_01711 HuMAP2_02451 |
| EPN3 | HuMAP2_00145 HuMAP2_01711 HuMAP2_03545 HuMAP2_04391 HuMAP2_05841 HuMAP2_05939 HuMAP2_06942 |