hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01712
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| H2BC1 | Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B) | UniProt NCBI |
| ZNHIT1 | Zinc finger HIT domain-containing protein 1 (Cyclin-G1-binding protein 1) (Zinc finger protein subfamily 4A member 1) (p18 Hamlet) | UniProt NCBI |
| H2BC13 | Histone H2B type 1-L (Histone H2B.c) (H2B/c) | UniProt NCBI |
| ACTR6 | Actin-related protein 6 (hArp6) (hARPX) | UniProt NCBI |
| MIER1 | Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1) | UniProt NCBI |
| BAHD1 | Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0006325 | 0.000173639558286 | 1.0 | ACTR6 H2BC1 ZNHIT1 MIER1 BAHD1 H2BC13 | chromatin organization |
| CORUM:304 | 0.000377010054596 | 0.333333333333 | ACTR6 ZNHIT1 | SRCAP-associated chromatin remodeling complex |
| GO:0051276 | 0.00288133296855 | 1.0 | ACTR6 H2BC1 ZNHIT1 MIER1 BAHD1 H2BC13 | chromosome organization |
| GO:0006338 | 0.00749584675125 | 0.666666666667 | BAHD1 ZNHIT1 ACTR6 H2BC1 | chromatin remodeling |
| GO:0034728 | 0.00769760366442 | 0.666666666667 | H2BC13 ZNHIT1 ACTR6 H2BC1 | nucleosome organization |
| REAC:R-HSA-171306 | 0.0280217040903 | 0.333333333333 | H2BC1 H2BC13 | Packaging Of Telomere Ends |
| REAC:R-HSA-110330 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Recognition and association of DNA glycosylase with site containing an affected purine |
| REAC:R-HSA-110331 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Cleavage of the damaged purine |
| REAC:R-HSA-73927 | 0.0314333263146 | 0.333333333333 | H2BC1 H2BC13 | Depurination |
| REAC:R-HSA-8866654 | 0.0338154872995 | 0.333333333333 | H2BC1 H2BC13 | E3 ubiquitin ligases ubiquitinate target proteins |
| REAC:R-HSA-110328 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Recognition and association of DNA glycosylase with site containing an affected pyrimidine |
| REAC:R-HSA-73928 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Depyrimidination |
| REAC:R-HSA-110329 | 0.036283735834 | 0.333333333333 | H2BC1 H2BC13 | Cleavage of the damaged pyrimidine |
| REAC:R-HSA-73929 | 0.0375501136505 | 0.333333333333 | H2BC1 H2BC13 | Base-Excision Repair, AP Site Formation |
| KEGG:05322 | 0.0388413362769 | 0.333333333333 | H2BC1 H2BC13 | Systemic lupus erythematosus |
| REAC:R-HSA-73728 | 0.0414781208299 | 0.333333333333 | H2BC1 H2BC13 | RNA Polymerase I Promoter Opening |
| REAC:R-HSA-5334118 | 0.0442040700727 | 0.333333333333 | H2BC1 H2BC13 | DNA methylation |
| GO:0071824 | 0.044962481783 | 0.666666666667 | H2BC13 ZNHIT1 ACTR6 H2BC1 | protein-DNA complex subunit organization |
| REAC:R-HSA-5625886 | 0.0470157324282 | 0.333333333333 | H2BC1 H2BC13 | Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 |
| REAC:R-HSA-427359 | 0.0484536768126 | 0.333333333333 | H2BC1 H2BC13 | SIRT1 negatively regulates rRNA expression |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MIER1 | H2BC1 | 0.999 | 0.949 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | BAHD1 | 0.998 | 0.942 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | H2BC13 | 0.94 | 0.852 | bioplex (H2BC1) bioplex_WMM |
| H2BC1 | ZNHIT1 | 0.844 | 0.788 | bioplex (H2BC1) bioplex_WMM |
| ZNHIT1 | ACTR6 | 0.77 | 0.749 | hein_WMM bioplex (ACTR6) bioplex_WMM |
| H2BC1 | ACTR6 | 0.714 | 0.727 | bioplex (H2BC1) bioplex_WMM |
| MIER1 | BAHD1 | 0.01 | 0.121 | bioplex_WMM WMM_only |
| BAHD1 | ZNHIT1 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| BAHD1 | H2BC13 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| BAHD1 | ACTR6 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| MIER1 | ZNHIT1 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| H2BC13 | ZNHIT1 | 0.008 | 0.014 | bioplex_WMM WMM_only |
| MIER1 | H2BC13 | 0.008 | 0.014 | bioplex_WMM WMM_only |
| MIER1 | ACTR6 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| H2BC13 | ACTR6 | 0.007 | 0.009 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01712 has an average edge precision of 0.363 which is ranked 3717 out of all 6965 complexes.
Related Complexes