hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01720
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STK25 | Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1) | UniProt NCBI |
| STK26 | Serine/threonine-protein kinase 26 (EC 2.7.11.1) (MST3 and SOK1-related kinase) (Mammalian STE20-like protein kinase 4) (MST-4) (STE20-like kinase MST4) (Serine/threonine-protein kinase MASK) | UniProt NCBI |
| PDCD10 | Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0036474 | 6.17566316957e-05 | 1.0 | PDCD10 STK25 STK26 | cell death in response to hydrogen peroxide |
| GO:0070301 | 0.00128871559377 | 1.0 | PDCD10 STK25 STK26 | cellular response to hydrogen peroxide |
| GO:0036473 | 0.00225266395968 | 1.0 | PDCD10 STK25 STK26 | cell death in response to oxidative stress |
| GO:0042542 | 0.00295242108794 | 1.0 | PDCD10 STK25 STK26 | response to hydrogen peroxide |
| GO:0071236 | 0.0051907357126 | 1.0 | PDCD10 STK25 STK26 | cellular response to antibiotic |
| GO:0036481 | 0.00811409485621 | 0.666666666667 | STK25 PDCD10 | intrinsic apoptotic signaling pathway in response to hydrogen peroxide |
| GO:0090168 | 0.00811409485621 | 0.666666666667 | STK25 PDCD10 | Golgi reassembly |
| GO:0097237 | 0.0106693663112 | 1.0 | PDCD10 STK25 STK26 | cellular response to toxic substance |
| GO:0034614 | 0.011404996777 | 1.0 | PDCD10 STK25 STK26 | cellular response to reactive oxygen species |
| GO:0046677 | 0.0190659069388 | 1.0 | PDCD10 STK25 STK26 | response to antibiotic |
| GO:0000302 | 0.022423560513 | 1.0 | PDCD10 STK25 STK26 | response to reactive oxygen species |
| GO:0010421 | 0.0283955176165 | 0.666666666667 | STK25 PDCD10 | hydrogen peroxide-mediated programmed cell death |
| GO:0097468 | 0.0283955176165 | 0.666666666667 | STK25 PDCD10 | programmed cell death in response to reactive oxygen species |
| GO:0051683 | 0.0378589948753 | 0.666666666667 | STK25 PDCD10 | establishment of Golgi localization |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STK25 | STK26 | 1.0 | 0.949 | bioplex (STK25) bioplex_WMM |
| STK26 | PDCD10 | 1.0 | 0.949 | hein_WMM bioplex (PDCD10) bioplex_WMM Malo fraction |
| STK25 | PDCD10 | 0.999 | 0.949 | bioplex (PDCD10,STK25) bioplex_WMM Malo fraction |
Images
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Complex HuMAP2_01720 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| STK25 | HuMAP2_00795 HuMAP2_00857 HuMAP2_01720 HuMAP2_04545 HuMAP2_06172 HuMAP2_06914 |
| STK26 | HuMAP2_00857 HuMAP2_01720 HuMAP2_06172 HuMAP2_06914 |
| PDCD10 | HuMAP2_00857 HuMAP2_01720 HuMAP2_06172 HuMAP2_06914 |