hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01744
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ACOT13 | Acyl-coenzyme A thioesterase 13 (Acyl-CoA thioesterase 13) (EC 3.1.2.-) (Thioesterase superfamily member 2) [Cleaved into: Acyl-coenzyme A thioesterase 13, N-terminally processed] | UniProt NCBI |
| EHD3 | EH domain-containing protein 3 (PAST homolog 3) | UniProt NCBI |
| VPS45 | Vacuolar protein sorting-associated protein 45 (h-VPS45) (hlVps45) | UniProt NCBI |
| HDDC3 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 (EC 3.1.7.2) (HD domain-containing protein 3) (Metazoan SpoT homolog 1) (MESH1) (Penta-phosphate guanosine-3'-pyrophosphohydrolase) ((ppGpp)ase) | UniProt NCBI |
| RBSN | Rabenosyn-5 (110 kDa protein) (FYVE finger-containing Rab5 effector protein rabenosyn-5) (RAB effector RBSN) (Zinc finger FYVE domain-containing protein 20) | UniProt NCBI |
| STX16 | Syntaxin-16 (Syn16) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04144 | 0.00329433483006 | 0.5 | RBSN EHD3 VPS45 | Endocytosis |
| REAC:R-HSA-983231 | 0.00382327070463 | 0.5 | RBSN EHD3 VPS45 | Factors involved in megakaryocyte development and platelet production |
| REAC:R-HSA-6811438 | 0.0208171179433 | 0.333333333333 | STX16 VPS45 | Intra-Golgi traffic |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| VPS45 | RBSN | 0.987 | 0.901 | bioplex (RBSN,VPS45) bioplex_WMM youn_WMM Malo gupta_WMM fraction boldt_WMM |
| VPS45 | STX16 | 0.703 | 0.723 | bioplex (VPS45) bioplex_WMM youn_WMM gupta_WMM boldt_WMM |
| RBSN | EHD3 | 0.191 | 0.444 | bioplex (RBSN) bioplex_WMM |
| VPS45 | ACOT13 | 0.094 | 0.357 | fraction |
| HDDC3 | ACOT13 | 0.041 | 0.271 | fraction |
| STX16 | RBSN | 0.008 | 0.066 | bioplex_WMM youn_WMM WMM_only |
| VPS45 | EHD3 | 0.008 | 0.066 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01744 has an average edge precision of 0.404 which is ranked 3278 out of all 6965 complexes.
Related Complexes