hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01749
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ARR3 | Arrestin-C (Cone arrestin) (C-arrestin) (cArr) (Retinal cone arrestin-3) (X-arrestin) | UniProt NCBI |
| ARRB2 | Beta-arrestin-2 (Arrestin beta-2) (Non-visual arrestin-3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002031 | 0.0162296428096 | 1.0 | ARRB2 ARR3 | G protein-coupled receptor internalization |
| GO:0002029 | 0.0247952876258 | 1.0 | ARRB2 ARR3 | desensitization of G protein-coupled receptor signaling pathway |
| GO:0022401 | 0.0247952876258 | 1.0 | ARRB2 ARR3 | negative adaptation of signaling pathway |
| GO:0023058 | 0.0247952876258 | 1.0 | ARRB2 ARR3 | adaptation of signaling pathway |
| CORUM:6805 | 0.0499173803268 | 0.5 | ARRB2 | S1PR1-beta-arrestin 2 complex, ApoM(+)HDL-S1P stimulated |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ARR3 | ARRB2 | 0.95 | 0.858 | bioplex (ARRB2) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_01749 has an average edge precision of 0.858 which is ranked 720 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ARR3 | HuMAP2_01749 HuMAP2_02112 HuMAP2_06012 |
| ARRB2 | HuMAP2_01749 HuMAP2_02112 HuMAP2_06012 |