hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01766
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAB3B | Ras-related protein Rab-3B | UniProt NCBI |
| RAB3A | Ras-related protein Rab-3A | UniProt NCBI |
| RAB39B | Ras-related protein Rab-39B | UniProt NCBI |
| SYTL4 | Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin) | UniProt NCBI |
| RAB33B | Ras-related protein Rab-33B | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8873719 | 2.03091825402e-07 | 0.8 | RAB33B RAB3A RAB3B RAB39B | RAB geranylgeranylation |
| GO:0032482 | 0.000118091273647 | 0.8 | RAB33B RAB3A RAB3B RAB39B | Rab protein signal transduction |
| GO:0031489 | 0.000330213415772 | 0.6 | RAB3A RAB3B RAB39B | myosin V binding |
| REAC:R-HSA-9007101 | 0.000681366686347 | 0.6 | RAB33B RAB3A RAB39B | Rab regulation of trafficking |
| GO:0017157 | 0.00125226429768 | 0.8 | RAB33B RAB3A RAB3B SYTL4 | regulation of exocytosis |
| GO:1905684 | 0.0135228859698 | 0.4 | RAB3A SYTL4 | regulation of plasma membrane repair |
| GO:0003924 | 0.0179259894308 | 0.8 | RAB33B RAB3A RAB3B RAB39B | GTPase activity |
| GO:0017022 | 0.0211681462149 | 0.6 | RAB3A RAB3B RAB39B | myosin binding |
| GO:0098993 | 0.0270421395626 | 0.4 | RAB3A RAB3B | anchored component of synaptic vesicle membrane |
| GO:0045054 | 0.0270421395626 | 0.4 | RAB3A RAB33B | constitutive secretory pathway |
| REAC:R-HSA-597592 | 0.035484350726 | 0.8 | RAB33B RAB3A RAB3B RAB39B | Post-translational protein modification |
| KEGG:04140 | 0.0370300962025 | 0.4 | RAB39B RAB33B | Autophagy - animal |
| GO:0007265 | 0.0376297096835 | 0.8 | RAB33B RAB3A RAB3B RAB39B | Ras protein signal transduction |
| REAC:R-HSA-8876198 | 0.0476518941102 | 0.4 | RAB3A RAB39B | RAB GEFs exchange GTP for GDP on RABs |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RAB3A | RAB3B | 1.0 | 0.949 | bioplex (RAB3A) bioplex_WMM |
| RAB3A | RAB33B | 0.755 | 0.748 | bioplex (RAB3A) bioplex_WMM |
| RAB3A | SYTL4 | 0.632 | 0.681 | bioplex (RAB3A) bioplex_WMM |
| RAB33B | RAB39B | 0.046 | 0.292 | bioplex (RAB39B) bioplex_WMM |
| RAB33B | SYTL4 | 0.009 | 0.112 | bioplex_WMM WMM_only |
| SYTL4 | RAB3B | 0.008 | 0.066 | bioplex_WMM WMM_only |
| RAB33B | RAB3B | 0.008 | 0.024 | bioplex_WMM WMM_only |
| RAB3B | RAB39B | 0.007 | 0.011 | bioplex_WMM WMM_only |
| RAB3A | RAB39B | 0.007 | 0.005 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01766 has an average edge precision of 0.321 which is ranked 4338 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAB3B | HuMAP2_01308 HuMAP2_01394 HuMAP2_01766 HuMAP2_05083 |
| RAB3A | HuMAP2_00453 HuMAP2_01308 HuMAP2_01394 HuMAP2_01766 HuMAP2_05083 |
| RAB39B | HuMAP2_01766 HuMAP2_02983 HuMAP2_03323 |
| SYTL4 | HuMAP2_01047 HuMAP2_01394 HuMAP2_01766 HuMAP2_05083 HuMAP2_06001 |
| RAB33B | HuMAP2_00453 HuMAP2_01308 HuMAP2_01394 HuMAP2_01766 HuMAP2_02053 HuMAP2_06911 |