hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_01767

Confidence: Medium

Genename	Protein Name	Links
ATP5PF	ATP synthase-coupling factor 6, mitochondrial (ATPase subunit F6) (ATP synthase peripheral stalk subunit F6)	UniProt NCBI
MT-ATP6	ATP synthase subunit a (F-ATPase protein 6)	UniProt NCBI
ATP5ME	ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed]	UniProt NCBI
ATP5MF	ATP synthase subunit f, mitochondrial (ATP synthase membrane subunit f)	UniProt NCBI
ATP5F1E	ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon)	UniProt NCBI
ATP5F1D	ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit)	UniProt NCBI
TAS2R41	Taste receptor type 2 member 41 (T2R41) (Taste receptor type 2 member 59) (T2R59)	UniProt NCBI
PIGM	GPI mannosyltransferase 1 (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:563	6.84589063872e-16	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	F1F0-ATP synthase, mitochondrial
REAC:R-HSA-163210	6.07647926777e-15	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Formation of ATP by chemiosmotic coupling
REAC:R-HSA-8949613	1.94089328445e-13	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Cristae formation
WP:WP623	2.6968852539e-12	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Oxidative phosphorylation
GO:0045259	3.57695311004e-12	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	proton-transporting ATP synthase complex
GO:0005753	3.57695311004e-12	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial proton-transporting ATP synthase complex
GO:0042776	9.31263837262e-12	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial ATP synthesis coupled proton transport
GO:0015985	1.24154200479e-11	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	energy coupled proton transport, down electrochemical gradient
GO:0015986	1.24154200479e-11	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ATP synthesis coupled proton transport
GO:0042407	5.47331906216e-11	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	cristae formation
WP:WP111	7.06002673687e-11	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Electron Transport Chain (OXPHOS system in mitochondria)
REAC:R-HSA-1592230	1.75960320758e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Mitochondrial biogenesis
GO:0006754	1.79420030701e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ATP biosynthetic process
GO:0009145	2.54240294583e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine nucleoside triphosphate biosynthetic process
GO:0009206	2.54240294583e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine ribonucleoside triphosphate biosynthetic process
KEGG:00190	2.8910281714e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Oxidative phosphorylation
GO:0009201	4.13944033826e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribonucleoside triphosphate biosynthetic process
GO:0016469	4.13944033826e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	proton-transporting two-sector ATPase complex
GO:0007007	4.8287898846e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	inner mitochondrial membrane organization
REAC:R-HSA-163200	9.60307528844e-10	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
GO:0009205	1.12882105879e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine ribonucleoside triphosphate metabolic process
GO:0009142	1.28618250729e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleoside triphosphate biosynthetic process
GO:0009199	1.6560647881e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribonucleoside triphosphate metabolic process
GO:0009144	1.87185712979e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine nucleoside triphosphate metabolic process
REAC:R-HSA-1428517	8.22692125664e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	The citric acid (TCA) cycle and respiratory electron transport
KEGG:04714	9.34727459319e-09	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Thermogenesis
GO:1902600	1.0045069602e-08	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	proton transmembrane transport
GO:0009141	1.10004716538e-08	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleoside triphosphate metabolic process
GO:1990542	5.32017018997e-08	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial transmembrane transport
GO:0007006	1.84966902863e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial membrane organization
REAC:R-HSA-1852241	1.97065650475e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Organelle biogenesis and maintenance
GO:0098800	2.43457652966e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	inner mitochondrial membrane protein complex
GO:0006119	3.16594855261e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	oxidative phosphorylation
GO:0009152	3.68653718824e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine ribonucleotide biosynthetic process
GO:0009260	5.1835889151e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribonucleotide biosynthetic process
GO:0046390	6.84071501416e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribose phosphate biosynthetic process
GO:0006164	6.84071501416e-07	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine nucleotide biosynthetic process
GO:0072522	1.10254229815e-06	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine-containing compound biosynthetic process
GO:0044455	3.80320479437e-06	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial membrane part
GO:0009165	3.93389230411e-06	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleotide biosynthetic process
GO:1901293	5.12037612393e-06	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleoside phosphate biosynthetic process
GO:0090407	7.54335900711e-06	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	organophosphate biosynthetic process
KEGG:01100	1.24026578075e-05	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	Metabolic pathways
GO:0006839	1.47806290067e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial transport
KEGG:05012	1.60085198137e-05	0.5	ATP5F1E MT-ATP6 ATP5F1D ATP5PF	Parkinson disease
GO:0098798	1.92422832206e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial protein complex
GO:1901137	2.00275631463e-05	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	carbohydrate derivative biosynthetic process
GO:0046034	2.07805732694e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ATP metabolic process
KEGG:05010	3.58216961585e-05	0.5	ATP5F1E MT-ATP6 ATP5F1D ATP5PF	Alzheimer disease
GO:0015672	5.5572513434e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	monovalent inorganic cation transport
KEGG:05016	6.11209889083e-05	0.5	ATP5F1E MT-ATP6 ATP5F1D ATP5PF	Huntington disease
GO:0009150	7.4620710198e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine ribonucleotide metabolic process
GO:0009259	8.95176330371e-05	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribonucleotide metabolic process
GO:0019693	0.000104759538979	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ribose phosphate metabolic process
GO:0016887	0.000113153670297	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ATPase activity
GO:0006163	0.000134101169945	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine nucleotide metabolic process
GO:0072521	0.000199210173457	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	purine-containing compound metabolic process
GO:0005743	0.000252926140752	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial inner membrane
GO:0006091	0.000328533709948	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	generation of precursor metabolites and energy
GO:0019866	0.000403001091552	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	organelle inner membrane
GO:0019637	0.000405713403794	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	organophosphate metabolic process
GO:0009117	0.000409266257129	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleotide metabolic process
GO:0006753	0.000441819215051	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleoside phosphate metabolic process
GO:0007005	0.000705245860279	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrion organization
GO:0017144	0.000735496977687	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	drug metabolic process
GO:0098662	0.000745816969302	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	inorganic cation transmembrane transport
GO:1901135	0.000750527359192	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	carbohydrate derivative metabolic process
GO:0098660	0.0011164170729	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	inorganic ion transmembrane transport
GO:0055086	0.00116065713307	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleobase-containing small molecule metabolic process
GO:0098655	0.00153172802551	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	cation transmembrane transport
GO:0031966	0.00160875341423	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial membrane
GO:0005740	0.00237579866466	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial envelope
GO:0017111	0.00427281124245	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	nucleoside-triphosphatase activity
GO:0016462	0.00637283867876	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	pyrophosphatase activity
GO:0061024	0.0064346523694	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	membrane organization
GO:0016817	0.0064969623439	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	hydrolase activity, acting on acid anhydrides
GO:0016818	0.0064969623439	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0034220	0.00986839361656	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	ion transmembrane transport
GO:0006812	0.0113706547175	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	cation transport
GO:0022857	0.0157114233078	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	transmembrane transporter activity
REAC:R-HSA-1430728	0.0157286835681	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	Metabolism
HP:0003287	0.0177949762727	0.375	ATP5F1E ATP5F1D MT-ATP6	Abnormality of mitochondrial metabolism
GO:1901566	0.0204217705349	0.875	ATP5ME ATP5F1D ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	organonitrogen compound biosynthetic process
HP:0003535	0.0224977761754	0.25	ATP5F1E ATP5F1D	3-Methylglutaconic aciduria
HP:0025354	0.0243320035336	0.5	ATP5F1E MT-ATP6 ATP5F1D PIGM	Abnormal cellular phenotype
GO:0044429	0.0283400474726	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	mitochondrial part
HP:0012103	0.0301849509731	0.375	ATP5F1E ATP5F1D MT-ATP6	Abnormality of the mitochondrion
GO:0005215	0.0350656249177	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	transporter activity
GO:0031975	0.0353191974108	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	envelope
GO:0031967	0.0353191974108	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	organelle envelope
KEGG:00000	0.045111549543	1.0	ATP5ME ATP5F1D TAS2R41 ATP5F1E PIGM ATP5MF MT-ATP6 ATP5PF	KEGG root term
GO:0098796	0.048081979475	0.75	ATP5ME ATP5F1D ATP5F1E ATP5MF MT-ATP6 ATP5PF	membrane protein complex

Edges

Protein 1	Protein 2	Score	Precision	Evidence
ATP5F1D	ATP5F1E	0.998	0.939	hein_WMM bioplex (ATP5F1D) bioplex_WMM Guru boldt fraction boldt_WMM
ATP5PF	ATP5F1D	0.922	0.843	hein_WMM bioplex (ATP5F1D) bioplex_WMM Guru fraction
ATP5F1D	ATP5MF	0.56	0.65	bioplex (ATP5F1D) bioplex_WMM Guru boldt fraction boldt_WMM
ATP5ME	ATP5F1D	0.558	0.649	hein_WMM bioplex (ATP5F1D) bioplex_WMM Guru boldt fraction boldt_WMM
ATP5ME	ATP5PF	0.483	0.613	bioplex_WMM Guru fraction
ATP5PF	ATP5F1E	0.365	0.544	hein_WMM bioplex_WMM Guru fraction
ATP5ME	ATP5F1E	0.041	0.271	hein_WMM bioplex_WMM Guru boldt fraction boldt_WMM
ATP5ME	PIGM	0.027	0.224	bioplex (PIGM) bioplex_WMM
ATP5F1D	MT-ATP6	0.025	0.213	bioplex (ATP5F1D) bioplex_WMM boldt boldt_WMM
ATP5ME	TAS2R41	0.022	0.196	bioplex (TAS2R41) bioplex_WMM
ATP5ME	MT-ATP6	0.013	0.148	bioplex_WMM boldt boldt_WMM
ATP5PF	MT-ATP6	0.012	0.149	bioplex_WMM WMM_only
ATP5MF	MT-ATP6	0.008	0.091	hein_WMM bioplex_WMM boldt youn_WMM boldt_WMM
ATP5MF	ATP5F1E	0.008	0.085	bioplex_WMM boldt boldt_WMM
ATP5PF	TAS2R41	0.008	0.06	bioplex (TAS2R41) bioplex_WMM
ATP5ME	ATP5MF	0.008	0.023	bioplex_WMM boldt boldt_WMM
ATP5F1D	TAS2R41	0.007	0.007	bioplex (TAS2R41) bioplex_WMM
ATP5F1E	MT-ATP6	0.007	0.0	hein_WMM bioplex_WMM WMM_only boldt_WMM
PIGM	MT-ATP6	0.007	0.003	bioplex_WMM WMM_only
ATP5PF	ATP5MF	0.007	0.007	bioplex_WMM youn_WMM WMM_only
ATP5MF	PIGM	0.005	0.007	bioplex_WMM WMM_only
ATP5PF	PIGM	0.005	0.005	bioplex (PIGM) bioplex_WMM
ATP5F1D	PIGM	0.005	0.006	bioplex (PIGM) bioplex_WMM
ATP5F1E	TAS2R41	0.005	0.008	bioplex (TAS2R41) bioplex_WMM
ATP5F1E	PIGM	0.005	0.013	bioplex (PIGM) bioplex_WMM

Images

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Complex HuMAP2_01767 has an average edge precision of 0.23 which is ranked 5694 out of all 6965 complexes.

Related Complexes

Genename	Complexes
ATP5PF	HuMAP2_00218 HuMAP2_01266 HuMAP2_01767 HuMAP2_02410 HuMAP2_03970 HuMAP2_04624 HuMAP2_05503 HuMAP2_05883 HuMAP2_06081
MT-ATP6	HuMAP2_01767 HuMAP2_03970 HuMAP2_05503 HuMAP2_06081
ATP5ME	HuMAP2_00218 HuMAP2_01266 HuMAP2_01767 HuMAP2_02410 HuMAP2_03970 HuMAP2_04624 HuMAP2_05503 HuMAP2_05883 HuMAP2_06081
ATP5MF	HuMAP2_01266 HuMAP2_01767 HuMAP2_02410 HuMAP2_03970 HuMAP2_05883 HuMAP2_06081
ATP5F1E	HuMAP2_01266 HuMAP2_01767 HuMAP2_02410 HuMAP2_03970 HuMAP2_05503 HuMAP2_05883 HuMAP2_06081
ATP5F1D	HuMAP2_00218 HuMAP2_01266 HuMAP2_01767 HuMAP2_02410 HuMAP2_03970 HuMAP2_04624 HuMAP2_05503 HuMAP2_05883 HuMAP2_06081
TAS2R41	HuMAP2_01767 HuMAP2_03970 HuMAP2_05503 HuMAP2_06081
PIGM	HuMAP2_01767 HuMAP2_03970 HuMAP2_05503 HuMAP2_06081

hu.MAP 2.0: Complex View

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Complex: HuMAP2_01767