hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01774
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NFYB | Nuclear transcription factor Y subunit beta (CAAT box DNA-binding protein subunit B) (Nuclear transcription factor Y subunit B) (NF-YB) | UniProt NCBI |
| NFYC | Nuclear transcription factor Y subunit gamma (CAAT box DNA-binding protein subunit C) (Nuclear transcription factor Y subunit C) (NF-YC) (Transactivator HSM-1/2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:4478 | 5.02777038712e-06 | 1.0 | NFYB NFYC | CBF-DNA complex |
| CORUM:4498 | 1.00555407742e-05 | 1.0 | NFYB NFYC | p32-CBF-DNA complex |
| REAC:R-HSA-381183 | 6.03332446455e-05 | 1.0 | NFYB NFYC | ATF6 (ATF6-alpha) activates chaperone genes |
| REAC:R-HSA-381033 | 9.21757904306e-05 | 1.0 | NFYB NFYC | ATF6 (ATF6-alpha) activates chaperones |
| REAC:R-HSA-9614657 | 0.000175971963549 | 1.0 | NFYB NFYC | FOXO-mediated transcription of cell death genes |
| KEGG:04612 | 0.000208779385658 | 1.0 | NFYB NFYC | Antigen processing and presentation |
| REAC:R-HSA-380994 | 0.000462554875615 | 1.0 | NFYB NFYC | ATF4 activates genes in response to endoplasmic reticulum stress |
| REAC:R-HSA-381042 | 0.000680424925724 | 1.0 | NFYB NFYC | PERK regulates gene expression |
| REAC:R-HSA-2426168 | 0.00117817419405 | 1.0 | NFYB NFYC | Activation of gene expression by SREBF (SREBP) |
| KEGG:05152 | 0.00163040505571 | 1.0 | NFYB NFYC | Tuberculosis |
| REAC:R-HSA-1655829 | 0.00205300624141 | 1.0 | NFYB NFYC | Regulation of cholesterol biosynthesis by SREBP (SREBF) |
| GO:0016602 | 0.00270494046827 | 1.0 | NFYB NFYC | CCAAT-binding factor complex |
| REAC:R-HSA-9614085 | 0.00277030148331 | 1.0 | NFYB NFYC | FOXO-mediated transcription |
| REAC:R-HSA-381119 | 0.00570316754246 | 1.0 | NFYB NFYC | Unfolded Protein Response (UPR) |
| REAC:R-HSA-1989781 | 0.00932651406811 | 1.0 | NFYB NFYC | PPARA activates gene expression |
| REAC:R-HSA-400206 | 0.00950416195513 | 1.0 | NFYB NFYC | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) |
| REAC:R-HSA-8957322 | 0.0131978972662 | 1.0 | NFYB NFYC | Metabolism of steroids |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NFYB | NFYC | 1.0 | 0.949 | hein_WMM bioplex (NFYC) bioplex_WMM Guru hein (NFYB,NFYC) Malo fraction |
Images
Click to enlarge
Complex HuMAP2_01774 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NFYB | HuMAP2_00188 HuMAP2_01706 HuMAP2_01774 HuMAP2_04445 HuMAP2_05672 HuMAP2_06896 |
| NFYC | HuMAP2_00188 HuMAP2_01774 HuMAP2_05672 HuMAP2_06896 |