hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01778
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRAPPC4 | Trafficking protein particle complex subunit 4 (Hematopoietic stem/progenitor cell protein 172) (Synbindin) (TRS23 homolog) | UniProt NCBI |
| TRAPPC12 | Trafficking protein particle complex subunit 12 (Tetratricopeptide repeat protein 15) (TPR repeat protein 15) (TTC-15) (Trafficking of membranes and mitosis) | UniProt NCBI |
| TRAPPC1 | Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6468 | 4.95783789704e-08 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | TRAPP complex |
| GO:0030008 | 1.08982291228e-05 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | TRAPP complex |
| REAC:R-HSA-8876198 | 4.44066869e-05 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | RAB GEFs exchange GTP for GDP on RABs |
| REAC:R-HSA-9007101 | 0.000113954833063 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | Rab regulation of trafficking |
| GO:0099023 | 0.00251749092736 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | vesicle tethering complex |
| REAC:R-HSA-204005 | 0.012220214888 | 0.666666666667 | TRAPPC1 TRAPPC4 | COPII-mediated vesicle transport |
| REAC:R-HSA-199991 | 0.0146202486223 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0171761243356 | 1.0 | TRAPPC1 TRAPPC12 TRAPPC4 | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TRAPPC1 | TRAPPC4 | 0.967 | 0.877 | bioplex (TRAPPC1) bioplex_WMM boldt boldt_WMM |
| TRAPPC1 | TRAPPC12 | 0.918 | 0.841 | hein_WMM bioplex (TRAPPC1,TRAPPC12) bioplex_WMM |
| TRAPPC4 | TRAPPC12 | 0.147 | 0.408 | bioplex (TRAPPC12) bioplex_WMM |
Images
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Complex HuMAP2_01778 has an average edge precision of 0.709 which is ranked 1347 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRAPPC4 | HuMAP2_00881 HuMAP2_01778 HuMAP2_04386 |
| TRAPPC12 | HuMAP2_00881 HuMAP2_01778 |
| TRAPPC1 | HuMAP2_00881 HuMAP2_01778 HuMAP2_04386 |