hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
SARAF	Store-operated calcium entry-associated regulatory factor (SARAF) (SOCE-associated regulatory factor) (HBV X-transactivated gene 3 protein) (HBV XAg-transactivated protein 3) (Protein FOAP-7) (Transmembrane protein 66)	UniProt NCBI
DERL2	Derlin-2 (Degradation in endoplasmic reticulum protein 2) (DERtrin-2) (Der1-like protein 2) (F-LAN-1) (F-LANa)	UniProt NCBI
FAF2	FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8)	UniProt NCBI
CCDC90B	Coiled-coil domain-containing protein 90B, mitochondrial	UniProt NCBI
STOM	Erythrocyte band 7 integral membrane protein (Protein 7.2b) (Stomatin)	UniProt NCBI
UBAC2	Ubiquitin-associated domain-containing protein 2 (UBA domain-containing protein 2) (Phosphoglycerate dehydrogenase-like protein 1)	UniProt NCBI
MCUR1	Mitochondrial calcium uniporter regulator 1 (MCU regulator 1) (Coiled-coil domain-containing protein 90A, mitochondrial)	UniProt NCBI
VRK2	Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:6859	0.000908974898571	0.25	FAF2 DERL2	HRD1 complex
GO:0030970	0.0147863948461	0.375	FAF2 DERL2 UBAC2	retrograde protein transport, ER to cytosol
GO:1903513	0.0147863948461	0.375	FAF2 DERL2 UBAC2	endoplasmic reticulum to cytosol transport
GO:0032527	0.0497817121827	0.375	FAF2 DERL2 UBAC2	protein exit from endoplasmic reticulum

Protein 1	Protein 2	Score	Precision	Evidence
CCDC90B	MCUR1	0.996	0.926	bioplex (CCDC90B,MCUR1) bioplex_WMM
MCUR1	FAF2	0.262	0.482	bioplex (FAF2) bioplex_WMM
DERL2	FAF2	0.13	0.399	bioplex (FAF2) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM
SARAF	FAF2	0.072	0.353	bioplex (FAF2) bioplex_WMM
STOM	FAF2	0.042	0.27	hein_WMM bioplex (FAF2) bioplex_WMM boldt (STOM) youn_WMM gupta_WMM boldt_WMM
UBAC2	FAF2	0.035	0.266	hein_WMM bioplex (FAF2,UBAC2) bioplex_WMM boldt youn_WMM boldt_WMM
VRK2	FAF2	0.033	0.254	bioplex (FAF2) bioplex_WMM youn_WMM gupta_WMM
MCUR1	SARAF	0.008	0.015	bioplex_WMM WMM_only
UBAC2	MCUR1	0.007	0.004	bioplex_WMM WMM_only
STOM	MCUR1	0.007	0.0	bioplex_WMM WMM_only
VRK2	MCUR1	0.007	0.002	bioplex_WMM WMM_only
DERL2	MCUR1	0.007	0.004	bioplex_WMM WMM_only
DERL2	SARAF	0.006	0.003	hein_WMM bioplex_WMM WMM_only
VRK2	SARAF	0.006	0.002	bioplex_WMM WMM_only
UBAC2	SARAF	0.006	0.007	hein_WMM bioplex_WMM WMM_only
STOM	SARAF	0.006	0.006	hein_WMM bioplex_WMM WMM_only
STOM	VRK2	0.004	0.009	bioplex_WMM youn_WMM gupta_WMM WMM_only
STOM	DERL2	0.003	0.013	bioplex_WMM boldt (STOM) boldt_WMM
STOM	UBAC2	0.003	0.014	hein_WMM bioplex_WMM boldt (STOM) youn_WMM boldt_WMM
DERL2	UBAC2	0.003	0.015	bioplex_WMM boldt youn_WMM boldt_WMM
VRK2	DERL2	0.0	0.016	bioplex_WMM gupta_WMM WMM_only
VRK2	UBAC2	0.0	0.011	bioplex_WMM youn_WMM WMM_only

Click to enlarge

Complex HuMAP2_01801 has an average edge precision of 0.14 which is ranked 6776 out of all 6965 complexes.