hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01809
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HMBS | Porphobilinogen deaminase (PBG-D) (EC 2.5.1.61) (Hydroxymethylbilane synthase) (HMBS) (Pre-uroporphyrinogen synthase) | UniProt NCBI |
| BSCL2 | Seipin (Bernardinelli-Seip congenital lipodystrophy type 2 protein) | UniProt NCBI |
| GABRE | Gamma-aminobutyric acid receptor subunit epsilon (GABA(A) receptor subunit epsilon) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003077 | 0.0307019877242 | 0.666666666667 | BSCL2 HMBS | Hyperlipidemia |
| CORUM:6088 | 0.0499776345577 | 0.333333333333 | BSCL2 | Seipin-AGPAT2 complex |
| CORUM:6090 | 0.0499776345577 | 0.333333333333 | BSCL2 | Seipin-lipin1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BSCL2 | GABRE | 0.054 | 0.303 | bioplex (GABRE) bioplex_WMM |
| GABRE | HMBS | 0.021 | 0.192 | bioplex (GABRE) bioplex_WMM |
| BSCL2 | HMBS | 0.007 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01809 has an average edge precision of 0.166 which is ranked 6561 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HMBS | HuMAP2_01809 HuMAP2_03126 |
| BSCL2 | HuMAP2_01809 HuMAP2_05610 |
| GABRE | HuMAP2_01809 HuMAP2_05610 HuMAP2_06005 |