hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01815
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| EEF1A1 | Elongation factor 1-alpha 1 (EF-1-alpha-1) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7) | UniProt NCBI |
| EEF1B2 | Elongation factor 1-beta (EF-1-beta) | UniProt NCBI |
| VARS | Valine--tRNA ligase (EC 6.1.1.9) (Protein G7a) (Valyl-tRNA synthetase) (ValRS) | UniProt NCBI |
| EEF1D | Elongation factor 1-delta (EF-1-delta) (Antigen NY-CO-4) | UniProt NCBI |
| CARS | Cysteine--tRNA ligase, cytoplasmic (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72766 | 4.0494371971e-07 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | Translation |
| GO:0005853 | 9.08185760231e-07 | 0.6 | EEF1B2 EEF1A1 EEF1D | eukaryotic translation elongation factor 1 complex |
| WP:WP107 | 1.31231633883e-05 | 0.6 | EEF1B2 EEF1A1 EEF1D | Translation Factors |
| REAC:R-HSA-156842 | 0.000338412904811 | 0.6 | EEF1B2 EEF1A1 EEF1D | Eukaryotic Translation Elongation |
| GO:0006412 | 0.00235530637857 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | translation |
| GO:0043043 | 0.00293652212837 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | peptide biosynthetic process |
| REAC:R-HSA-379716 | 0.00371437175588 | 0.4 | VARS CARS | Cytosolic tRNA aminoacylation |
| REAC:R-HSA-392499 | 0.0039377533293 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | Metabolism of proteins |
| KEGG:00970 | 0.00403884103568 | 0.4 | VARS CARS | Aminoacyl-tRNA biosynthesis |
| GO:0043604 | 0.00727283691478 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | amide biosynthetic process |
| GO:0006518 | 0.00744517222081 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | peptide metabolic process |
| REAC:R-HSA-379724 | 0.0115592172394 | 0.4 | VARS CARS | tRNA Aminoacylation |
| HPA:009020_13 | 0.0136400669622 | 0.6 | EEF1B2 EEF1A1 EEF1D | cervix, uterine; squamous epithelial cells[Supported,High] |
| HPA:014020_13 | 0.0138986902566 | 0.6 | EEF1B2 EEF1A1 EEF1D | endometrium 2; glandular cells[Supported,High] |
| MIRNA:hsa-miR-93-3p | 0.0142310277096 | 0.6 | VARS EEF1A1 EEF1D | hsa-miR-93-3p |
| HPA:058010_13 | 0.0151025190567 | 0.6 | EEF1B2 EEF1A1 EEF1D | vagina; squamous epithelial cells[Supported,High] |
| HPA:040010_13 | 0.0165184888819 | 0.6 | EEF1B2 EEF1A1 EEF1D | seminal vesicle; glandular cells[Supported,High] |
| HPA:013020_13 | 0.0180192386998 | 0.6 | EEF1B2 EEF1A1 EEF1D | endometrium 1; glandular cells[Supported,High] |
| HPA:044010_13 | 0.0234185559543 | 0.6 | EEF1B2 EEF1A1 EEF1D | skin 2; epidermal cells[Supported,High] |
| HPA:039010_13 | 0.0236024900229 | 0.6 | EEF1B2 EEF1A1 EEF1D | salivary gland; glandular cells[Supported,High] |
| GO:0043603 | 0.0273795782463 | 1.0 | EEF1D EEF1B2 EEF1A1 CARS VARS | cellular amide metabolic process |
| HPA:016010_13 | 0.0293581469203 | 0.6 | EEF1B2 EEF1A1 EEF1D | esophagus; squamous epithelial cells[Supported,High] |
| HPA:009020_03 | 0.0397374089383 | 0.6 | EEF1B2 EEF1A1 EEF1D | cervix, uterine; squamous epithelial cells[Uncertain,High] |
| HPA:014010_12 | 0.0432077883482 | 0.6 | EEF1B2 EEF1A1 EEF1D | endometrium 2; cells in endometrial stroma[Supported,Medium] |
| HPA:057010_13 | 0.0437586981176 | 0.6 | EEF1B2 EEF1A1 EEF1D | urinary bladder; urothelial cells[Supported,High] |
| HPA:018010_13 | 0.0486283293616 | 0.6 | EEF1B2 EEF1A1 EEF1D | fallopian tube; glandular cells[Supported,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| EEF1B2 | EEF1A1 | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1) bioplex_WMM Guru boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| EEF1A1 | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1,EEF1D) bioplex_WMM boldt hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1A1 | 1.0 | 0.949 | hein_WMM bioplex (EEF1A1) bioplex_WMM hein (EEF1A1) Malo fraction boldt_WMM treiber_WMM |
| VARS | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1D) bioplex_WMM Malo gupta_WMM fraction boldt_WMM |
| EEF1B2 | VARS | 1.0 | 0.949 | hein_WMM bioplex_WMM Malo gupta_WMM fraction boldt_WMM |
| EEF1B2 | EEF1D | 1.0 | 0.949 | hein_WMM bioplex (EEF1D) bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| CARS | EEF1A1 | 0.741 | 0.74 | hein_WMM bioplex (EEF1A1) bioplex_WMM hein (EEF1A1) fraction boldt_WMM treiber_WMM |
| CARS | EEF1D | 0.32 | 0.512 | hein_WMM bioplex (EEF1D) bioplex_WMM boldt_WMM |
| CARS | EEF1B2 | 0.0 | 0.01 | hein_WMM bioplex_WMM fraction boldt_WMM |
| CARS | VARS | 0.0 | 0.001 | hein_WMM bioplex_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_01815 has an average edge precision of 0.696 which is ranked 1389 out of all 6965 complexes.
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