hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01821
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PGK1 | Phosphoglycerate kinase 1 (EC 2.7.2.3) (Cell migration-inducing gene 10 protein) (Primer recognition protein 2) (PRP 2) | UniProt NCBI |
| SERPINC1 | Antithrombin-III (ATIII) (Serpin C1) | UniProt NCBI |
| AKR1D1 | Aldo-keto reductase family 1 member D1 (EC 1.3.1.3) (3-oxo-5-beta-steroid 4-dehydrogenase) (Delta(4)-3-ketosteroid 5-beta-reductase) (Delta(4)-3-oxosteroid 5-beta-reductase) | UniProt NCBI |
| SERPINB12 | Serpin B12 | UniProt NCBI |
| TEX15 | NCBI | |
| SCP2 | Non-specific lipid-transfer protein (NSL-TP) (EC 2.3.1.176) (Propanoyl-CoA C-acyltransferase) (SCP-chi) (SCPX) (Sterol carrier protein 2) (SCP-2) (Sterol carrier protein X) (SCP-X) | UniProt NCBI |
| GPI | Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Sperm antigen 36) (SA-36) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP1946 | 0.000585450803921 | 0.333333333333 | GPI PGK1 | Cori Cycle |
| KEGG:00120 | 0.000655921734023 | 0.333333333333 | SCP2 AKR1D1 | Primary bile acid biosynthesis |
| WP:WP4290 | 0.00477752328717 | 0.333333333333 | GPI PGK1 | Metabolic reprogramming in colon cancer |
| WP:WP534 | 0.00524729006009 | 0.333333333333 | GPI PGK1 | Glycolysis and Gluconeogenesis |
| REAC:R-HSA-70263 | 0.00959640616298 | 0.333333333333 | GPI PGK1 | Gluconeogenesis |
| KEGG:00010 | 0.0120956152943 | 0.333333333333 | GPI PGK1 | Glycolysis / Gluconeogenesis |
| WP:WP4018 | 0.0174151198914 | 0.333333333333 | GPI PGK1 | Pathways in clear cell renal cell carcinoma |
| KEGG:01100 | 0.0331288091988 | 0.666666666667 | SCP2 GPI PGK1 AKR1D1 | Metabolic pathways |
| KEGG:01200 | 0.039527830217 | 0.333333333333 | GPI PGK1 | Carbon metabolism |
| REAC:R-HSA-70171 | 0.0470157324282 | 0.333333333333 | GPI PGK1 | Glycolysis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| AKR1D1 | GPI | 0.628 | 0.68 | bioplex (AKR1D1) fraction |
| SERPINB12 | GPI | 0.303 | 0.497 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| PGK1 | GPI | 0.226 | 0.467 | bioplex_WMM Guru boldt fraction boldt_WMM treiber_WMM |
| SERPINB12 | PGK1 | 0.1 | 0.362 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| SERPINC1 | PGK1 | 0.075 | 0.356 | fraction |
| PGK1 | AKR1D1 | 0.061 | 0.337 | bioplex (AKR1D1) fraction |
| SCP2 | GPI | 0.045 | 0.288 | bioplex (SCP2) bioplex_WMM fraction |
| SERPINC1 | GPI | 0.043 | 0.272 | bioplex (SERPINC1) fraction |
| TEX15 | SERPINC1 | 0.041 | 0.269 | bioplex (SERPINC1) bioplex_WMM |
| SERPINB12 | SCP2 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| SERPINB12 | TEX15 | 0.007 | 0.002 | WMM_only boldt_WMM |
| TEX15 | PGK1 | 0.007 | 0.002 | WMM_only boldt_WMM |
| TEX15 | SCP2 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| TEX15 | GPI | 0.007 | 0.005 | bioplex_WMM WMM_only |
| PGK1 | SCP2 | 0.0 | 0.0 | bioplex (SCP2) bioplex_WMM fraction |
| SCP2 | AKR1D1 | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_01821 has an average edge precision of 0.222 which is ranked 5828 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PGK1 | HuMAP2_01821 HuMAP2_03438 HuMAP2_04437 HuMAP2_06612 HuMAP2_06649 |
| SERPINC1 | HuMAP2_01120 HuMAP2_01821 HuMAP2_03142 HuMAP2_06491 |
| AKR1D1 | HuMAP2_01821 HuMAP2_03132 HuMAP2_03922 HuMAP2_04100 HuMAP2_05630 HuMAP2_06910 |
| SERPINB12 | HuMAP2_00025 HuMAP2_01821 |
| TEX15 | HuMAP2_01120 HuMAP2_01294 HuMAP2_01821 HuMAP2_03142 HuMAP2_06491 |
| SCP2 | HuMAP2_01821 |
| GPI | HuMAP2_01821 HuMAP2_03922 HuMAP2_04195 |