hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_01831

Confidence: Very High

Genename	Protein Name	Links
GNPDA1	Glucosamine-6-phosphate isomerase 1 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 1) (GNPDA 1) (GlcN6P deaminase 1) (Oscillin)	UniProt NCBI
AMDHD2	N-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase) (EC 3.5.1.25) (Amidohydrolase domain-containing protein 2)	UniProt NCBI
GNPDA2	Glucosamine-6-phosphate isomerase 2 (EC 3.5.99.6) (Glucosamine-6-phosphate deaminase 2) (GNPDA 2) (GlcN6P deaminase 2) (Glucosamine-6-phosphate isomerase SB52)	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0006046	9.08185760231e-08	1.0	GNPDA1 AMDHD2 GNPDA2	N-acetylglucosamine catabolic process
KEGG:00520	4.56498670209e-07	1.0	GNPDA1 AMDHD2 GNPDA2	Amino sugar and nucleotide sugar metabolism
GO:0019262	1.81637152046e-06	1.0	GNPDA1 AMDHD2 GNPDA2	N-acetylneuraminate catabolic process
GO:1901072	3.17865016081e-06	1.0	GNPDA1 AMDHD2 GNPDA2	glucosamine-containing compound catabolic process
GO:0006054	1.08982291228e-05	1.0	GNPDA1 AMDHD2 GNPDA2	N-acetylneuraminate metabolic process
GO:0046348	1.08982291228e-05	1.0	GNPDA1 AMDHD2 GNPDA2	amino sugar catabolic process
GO:0006048	1.49850650438e-05	1.0	GNPDA1 AMDHD2 GNPDA2	UDP-N-acetylglucosamine biosynthetic process
GO:0046349	1.99800867251e-05	1.0	GNPDA1 AMDHD2 GNPDA2	amino sugar biosynthetic process
GO:0006047	1.99800867251e-05	1.0	GNPDA1 AMDHD2 GNPDA2	UDP-N-acetylglucosamine metabolic process
GO:0006044	3.30579616724e-05	1.0	GNPDA1 AMDHD2 GNPDA2	N-acetylglucosamine metabolic process
GO:1901071	8.80032001664e-05	1.0	GNPDA1 AMDHD2 GNPDA2	glucosamine-containing compound metabolic process
GO:0009226	0.000139860607076	1.0	GNPDA1 AMDHD2 GNPDA2	nucleotide-sugar biosynthetic process
GO:0009225	0.000368723418654	1.0	GNPDA1 AMDHD2 GNPDA2	nucleotide-sugar metabolic process
GO:0006040	0.000495506150782	1.0	GNPDA1 AMDHD2 GNPDA2	amino sugar metabolic process
GO:0017001	0.000968126020406	1.0	GNPDA1 AMDHD2 GNPDA2	antibiotic catabolic process
GO:0006043	0.00135247023414	0.666666666667	GNPDA1 GNPDA2	glucosamine catabolic process
GO:0004342	0.00135247023414	0.666666666667	GNPDA1 GNPDA2	glucosamine-6-phosphate deaminase activity
GO:0006041	0.00405722906526	0.666666666667	GNPDA1 GNPDA2	glucosamine metabolic process
GO:0016999	0.00865355719779	1.0	GNPDA1 AMDHD2 GNPDA2	antibiotic metabolic process
KEGG:01100	0.0105851300972	1.0	GNPDA1 AMDHD2 GNPDA2	Metabolic pathways
REAC:R-HSA-70171	0.0143204798819	0.666666666667	GNPDA1 GNPDA2	Glycolysis
GO:0042737	0.0180261250619	1.0	GNPDA1 AMDHD2 GNPDA2	drug catabolic process
REAC:R-HSA-70326	0.022155781492	0.666666666667	GNPDA1 GNPDA2	Glucose metabolism
GO:0016861	0.0378589948753	0.666666666667	GNPDA1 GNPDA2	intramolecular oxidoreductase activity, interconverting aldoses and ketoses
GO:1901136	0.0406485782564	1.0	GNPDA1 AMDHD2 GNPDA2	carbohydrate derivative catabolic process
HPA:047020_03	0.044531062015	0.666666666667	GNPDA1 GNPDA2	soft tissue 1; chondrocytes[Uncertain,High]

Edges

Protein 1	Protein 2	Score	Precision	Evidence
GNPDA1	GNPDA2	1.0	0.949	bioplex (GNPDA1) bioplex_WMM
GNPDA1	AMDHD2	1.0	0.949	bioplex (GNPDA1) bioplex_WMM Malo fraction
GNPDA2	AMDHD2	0.168	0.425	bioplex_WMM Malo fraction

Images

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Complex HuMAP2_01831 has an average edge precision of 0.774 which is ranked 1019 out of all 6965 complexes.

Related Complexes

Genename	Complexes
GNPDA1	HuMAP2_00268 HuMAP2_00386 HuMAP2_01020 HuMAP2_01831
AMDHD2	HuMAP2_01020 HuMAP2_01831
GNPDA2	HuMAP2_00268 HuMAP2_01020 HuMAP2_01831

hu.MAP 2.0: Complex View

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Complex: HuMAP2_01831