hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01834
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR7 | WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG) | UniProt NCBI |
| DMXL2 | DmX-like protein 2 (Rabconnectin-3) | UniProt NCBI |
| ATP1A2 | Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2) | UniProt NCBI |
| DMXL1 | DmX-like protein 1 (X-like 1 protein) | UniProt NCBI |
| ROGDI | Protein rogdi homolog | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0043291 | 9.08185760231e-07 | 0.6 | DMXL1 DMXL2 ROGDI | RAVE complex |
| GO:0030004 | 0.000202099795148 | 0.8 | DMXL1 ATP1A2 DMXL2 ROGDI | cellular monovalent inorganic cation homeostasis |
| GO:0055067 | 0.0005799178998 | 0.8 | DMXL1 ATP1A2 DMXL2 ROGDI | monovalent inorganic cation homeostasis |
| GO:0007035 | 0.000878614215261 | 0.6 | DMXL1 DMXL2 ROGDI | vacuolar acidification |
| GO:0051452 | 0.00964423896068 | 0.6 | DMXL1 DMXL2 ROGDI | intracellular pH reduction |
| GO:0045851 | 0.0103850554114 | 0.6 | DMXL1 DMXL2 ROGDI | pH reduction |
| GO:0051453 | 0.0432266328844 | 0.6 | DMXL1 DMXL2 ROGDI | regulation of intracellular pH |
| GO:0030641 | 0.0472676873043 | 0.6 | DMXL1 DMXL2 ROGDI | regulation of cellular pH |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ROGDI | DMXL1 | 1.0 | 0.949 | bioplex (ROGDI) bioplex_WMM |
| ROGDI | WDR7 | 0.999 | 0.947 | bioplex (ROGDI) bioplex_WMM |
| DMXL2 | ROGDI | 0.968 | 0.88 | bioplex (ROGDI) bioplex_WMM |
| ROGDI | ATP1A2 | 0.541 | 0.641 | bioplex (ROGDI) bioplex_WMM gupta_WMM |
| WDR7 | DMXL1 | 0.012 | 0.15 | bioplex_WMM WMM_only |
| ATP1A2 | WDR7 | 0.008 | 0.089 | bioplex_WMM WMM_only |
| ATP1A2 | DMXL1 | 0.008 | 0.084 | bioplex_WMM WMM_only |
| DMXL2 | WDR7 | 0.008 | 0.081 | bioplex_WMM WMM_only |
| DMXL2 | DMXL1 | 0.008 | 0.075 | bioplex_WMM WMM_only |
| DMXL2 | ATP1A2 | 0.008 | 0.045 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01834 has an average edge precision of 0.394 which is ranked 3387 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR7 | HuMAP2_01834 HuMAP2_03388 |
| DMXL2 | HuMAP2_01148 HuMAP2_01834 HuMAP2_03388 |
| ATP1A2 | HuMAP2_01738 HuMAP2_01834 HuMAP2_02677 HuMAP2_04279 |
| DMXL1 | HuMAP2_01834 HuMAP2_03388 |
| ROGDI | HuMAP2_01148 HuMAP2_01834 HuMAP2_03388 |