hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01837
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IRF2BPL | Probable E3 ubiquitin-protein ligase IRF2BPL (EC 2.3.2.27) (Enhanced at puberty protein 1) (Interferon regulatory factor 2-binding protein-like) | UniProt NCBI |
| VGLL4 | Transcription cofactor vestigial-like protein 4 (Vgl-4) | UniProt NCBI |
| IRF2BP2 | Interferon regulatory factor 2-binding protein 2 (IRF-2-binding protein 2) (IRF-2BP2) | UniProt NCBI |
| IRF2BP1 | Interferon regulatory factor 2-binding protein 1 (IRF-2-binding protein 1) (IRF-2BP1) (Probable E3 ubiquitin-protein ligase IRF2BP1) (EC 2.3.2.27) (Probable RING-type E3 ubiquitin transferase IRF2BP1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6848 | 6.75231048499e-10 | 0.75 | IRF2BP1 IRF2BPL IRF2BP2 | IRF2BP2-IRF2BP1-IRF2BPL complex |
| HPA:031020_22 | 0.00240183798634 | 1.0 | IRF2BP1 VGLL4 IRF2BPL IRF2BP2 | ovary; ovarian stroma cells[Approved,Medium] |
| HPA:032020_23 | 0.00359313936294 | 0.75 | IRF2BP1 IRF2BPL IRF2BP2 | pancreas; islets of Langerhans[Approved,High] |
| HPA:008020_22 | 0.00688823541314 | 1.0 | IRF2BP1 VGLL4 IRF2BPL IRF2BP2 | cerebral cortex; glial cells[Approved,Medium] |
| HPA:007030_22 | 0.0170678309484 | 1.0 | IRF2BP1 VGLL4 IRF2BPL IRF2BP2 | cerebellum; cells in molecular layer[Approved,Medium] |
| HPA:046010_22 | 0.0244414942053 | 1.0 | IRF2BP1 VGLL4 IRF2BPL IRF2BP2 | smooth muscle; smooth muscle cells[Approved,Medium] |
| HPA:009020_22 | 0.0422306677852 | 1.0 | IRF2BP1 VGLL4 IRF2BPL IRF2BP2 | cervix, uterine; squamous epithelial cells[Approved,Medium] |
| HPA:031020_23 | 0.0431522217761 | 0.5 | IRF2BP1 IRF2BPL | ovary; ovarian stroma cells[Approved,High] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IRF2BP2 | VGLL4 | 1.0 | 0.949 | bioplex (VGLL4) bioplex_WMM |
| IRF2BPL | VGLL4 | 0.996 | 0.928 | bioplex (VGLL4) bioplex_WMM |
| IRF2BP1 | VGLL4 | 0.994 | 0.923 | bioplex (IRF2BP1,VGLL4) bioplex_WMM |
| IRF2BPL | IRF2BP2 | 0.352 | 0.539 | bioplex_WMM Malo fraction |
| IRF2BP1 | IRF2BPL | 0.137 | 0.408 | bioplex (IRF2BP1) bioplex_WMM |
| IRF2BP1 | IRF2BP2 | 0.091 | 0.354 | bioplex (IRF2BP1) bioplex_WMM youn_WMM |
Images
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Complex HuMAP2_01837 has an average edge precision of 0.683 which is ranked 1442 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IRF2BPL | HuMAP2_01837 HuMAP2_02068 HuMAP2_04016 HuMAP2_04843 |
| VGLL4 | HuMAP2_01837 HuMAP2_02068 HuMAP2_02569 HuMAP2_04011 HuMAP2_04016 HuMAP2_04843 |
| IRF2BP2 | HuMAP2_01837 HuMAP2_02068 HuMAP2_04016 HuMAP2_04843 HuMAP2_06180 |
| IRF2BP1 | HuMAP2_00684 HuMAP2_01837 HuMAP2_02068 HuMAP2_04016 HuMAP2_04843 HuMAP2_05903 HuMAP2_06520 |