hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01846
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| STX4 | Syntaxin-4 (Renal carcinoma antigen NY-REN-31) | UniProt NCBI |
| STXBP3 | Syntaxin-binding protein 3 (Platelet Sec1 protein) (PSP) (Protein unc-18 homolog 3) (Unc18-3) (Protein unc-18 homolog C) (Unc-18C) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-114516 | 1.67592346237e-05 | 1.0 | STX4 STXBP3 | Disinhibition of SNARE formation |
| REAC:R-HSA-1445148 | 0.00381775364729 | 1.0 | STX4 STXBP3 | Translocation of SLC2A4 (GLUT4) to the plasma membrane |
| WP:WP481 | 0.00438938066897 | 1.0 | STX4 STXBP3 | Insulin Signaling |
| REAC:R-HSA-76005 | 0.0109856782959 | 1.0 | STX4 STXBP3 | Response to elevated platelet cytosolic Ca2+ |
| REAC:R-HSA-76002 | 0.0414841334642 | 1.0 | STX4 STXBP3 | Platelet activation, signaling and aggregation |
| CORUM:730 | 0.0499173803268 | 0.5 | STX4 | SNARE complex (STX4, SNAP23, VAMP1) |
| CORUM:733 | 0.0499173803268 | 0.5 | STX4 | SNARE complex (STX4, VAMP1, VAMP7) |
| CORUM:805 | 0.0499173803268 | 0.5 | STX4 | SNARE complex (STX4, SNAP23) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STX4 | STXBP3 | 0.355 | 0.54 | bioplex (STXBP3) bioplex_WMM |
Images
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Complex HuMAP2_01846 has an average edge precision of 0.54 which is ranked 2268 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| STX4 | HuMAP2_00644 HuMAP2_01846 |
| STXBP3 | HuMAP2_01846 HuMAP2_01946 HuMAP2_04269 |