hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01858
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR48 | WD repeat-containing protein 48 (USP1-associated factor 1) (WD repeat endosomal protein) (p80) | UniProt NCBI |
| DMWD | Dystrophia myotonica WD repeat-containing protein (Dystrophia myotonica-containing WD repeat motif protein) (Protein 59) (Protein DMR-N9) | UniProt NCBI |
| USP46 | Ubiquitin carboxyl-terminal hydrolase 46 (EC 3.4.19.12) (Deubiquitinating enzyme 46) (Ubiquitin thioesterase 46) (Ubiquitin-specific-processing protease 46) | UniProt NCBI |
| WDR20 | WD repeat-containing protein 20 (Protein DMR) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6635 | 6.75231048499e-10 | 0.75 | WDR20 USP46 WDR48 | WDR20-USP46-UAF1 complex |
| CORUM:6637 | 5.02777038712e-06 | 0.5 | WDR48 USP46 | USP46-UAF1 complex |
| CORUM:6634 | 1.50819606993e-05 | 0.5 | WDR20 WDR48 | WDR20-USP12-UAF1 complex |
| CORUM:3176 | 0.0499140284799 | 0.25 | WDR48 | USP1-UAF1 complex |
| CORUM:6636 | 0.0499140284799 | 0.25 | WDR48 | USP12-UAF1 complex |
| CORUM:6638 | 0.0499140284799 | 0.25 | WDR48 | USP1-UAF1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WDR20 | WDR48 | 0.92 | 0.844 | hein_WMM bioplex (WDR20) bioplex_WMM boldt hein (WDR48) gupta_WMM boldt_WMM |
| USP46 | DMWD | 0.893 | 0.819 | bioplex (USP46) bioplex_WMM |
| USP46 | WDR48 | 0.72 | 0.732 | bioplex (USP46) bioplex_WMM boldt gupta_WMM boldt_WMM |
| USP46 | WDR20 | 0.67 | 0.704 | bioplex (USP46,WDR20) bioplex_WMM boldt gupta_WMM boldt_WMM |
| WDR20 | DMWD | 0.008 | 0.082 | hein_WMM bioplex_WMM WMM_only |
| WDR48 | DMWD | 0.006 | 0.003 | hein_WMM bioplex_WMM hein (WDR48) |
Images
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Complex HuMAP2_01858 has an average edge precision of 0.531 which is ranked 2331 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WDR48 | HuMAP2_01079 HuMAP2_01858 HuMAP2_04664 HuMAP2_05585 HuMAP2_06059 |
| DMWD | HuMAP2_01079 HuMAP2_01772 HuMAP2_01858 HuMAP2_06059 |
| USP46 | HuMAP2_01079 HuMAP2_01772 HuMAP2_01858 HuMAP2_06059 |
| WDR20 | HuMAP2_01079 HuMAP2_01858 HuMAP2_04145 HuMAP2_05585 HuMAP2_06059 |