hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01859
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| APPL1 | DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1) | UniProt NCBI |
| APPL2 | DCC-interacting protein 13-beta (Dip13-beta) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1905303 | 0.000450823411379 | 1.0 | APPL2 APPL1 | positive regulation of macropinocytosis |
| GO:1905301 | 0.00135247023414 | 1.0 | APPL2 APPL1 | regulation of macropinocytosis |
| GO:0048549 | 0.00270494046827 | 1.0 | APPL2 APPL1 | positive regulation of pinocytosis |
| GO:1905449 | 0.00450823411379 | 1.0 | APPL2 APPL1 | regulation of Fc-gamma receptor signaling pathway involved in phagocytosis |
| GO:0033211 | 0.00676235117068 | 1.0 | APPL2 APPL1 | adiponectin-activated signaling pathway |
| GO:0044352 | 0.00946729163895 | 1.0 | APPL2 APPL1 | pinosome |
| GO:0044354 | 0.00946729163895 | 1.0 | APPL2 APPL1 | macropinosome |
| GO:0060368 | 0.00946729163895 | 1.0 | APPL2 APPL1 | regulation of Fc receptor mediated stimulatory signaling pathway |
| GO:0032009 | 0.0126230555186 | 1.0 | APPL2 APPL1 | early phagosome |
| GO:0035728 | 0.0162296428096 | 1.0 | APPL2 APPL1 | response to hepatocyte growth factor |
| GO:0035729 | 0.0162296428096 | 1.0 | APPL2 APPL1 | cellular response to hepatocyte growth factor stimulus |
| GO:0044351 | 0.0162296428096 | 1.0 | APPL2 APPL1 | macropinocytosis |
| GO:0048548 | 0.0162296428096 | 1.0 | APPL2 APPL1 | regulation of pinocytosis |
| GO:0010762 | 0.0410249304355 | 1.0 | APPL2 APPL1 | regulation of fibroblast migration |
| GO:0010761 | 0.0473364581948 | 1.0 | APPL2 APPL1 | fibroblast migration |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| APPL2 | APPL1 | 0.109 | 0.373 | bioplex (APPL1,APPL2) bioplex_WMM gupta_WMM |
Images
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Complex HuMAP2_01859 has an average edge precision of 0.373 which is ranked 3603 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| APPL1 | HuMAP2_01859 HuMAP2_05294 |
| APPL2 | HuMAP2_01859 |