hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01882
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CAND1 | Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1) | UniProt NCBI |
| ECPAS | Proteasome adapter and scaffold protein ECM29 (Ecm29 proteasome adapter and scaffold) (Proteasome-associated protein ECM29 homolog) | UniProt NCBI |
| CAND2 | Cullin-associated NEDD8-dissociated protein 2 (Cullin-associated and neddylation-dissociated protein 2) (Epididymis tissue protein Li 169) (TBP-interacting protein of 120 kDa B) (TBP-interacting protein 120B) (p120 CAND2) | UniProt NCBI |
| FBXL15 | F-box/LRR-repeat protein 15 (F-box only protein 37) | UniProt NCBI |
| CUL1 | Cullin-1 (CUL-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0010265 | 1.81582264982e-05 | 0.6 | CUL1 CAND2 CAND1 | SCF complex assembly |
| CORUM:219 | 2.0123342217e-05 | 0.4 | CAND1 CUL1 | CAND1-CUL1-RBX1 complex |
| REAC:R-HSA-8951664 | 0.00478425526644 | 0.6 | CUL1 FBXL15 CAND1 | Neddylation |
| REAC:R-HSA-917937 | 0.019180674733 | 0.4 | CAND1 CUL1 | Iron uptake and transport |
| CORUM:2714 | 0.0499494897235 | 0.2 | CUL1 | Ubiquitin E3 ligase (CHEK1, CUL1) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CUL1 | CAND1 | 0.218 | 0.466 | hein_WMM bioplex_WMM hein (CUL1) gupta_WMM fraction treiber_WMM |
| CAND2 | CAND1 | 0.117 | 0.39 | bioplex_WMM boldt fraction boldt_WMM |
| FBXL15 | CUL1 | 0.1 | 0.361 | hein_WMM bioplex (FBXL15) bioplex_WMM |
| ECPAS | CAND1 | 0.047 | 0.294 | bioplex_WMM boldt gupta_WMM fraction boldt_WMM treiber_WMM |
| CUL1 | ECPAS | 0.007 | 0.003 | bioplex_WMM youn_WMM WMM_only |
| ECPAS | CAND2 | 0.0 | 0.008 | bioplex_WMM boldt fraction boldt_WMM |
Images
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Complex HuMAP2_01882 has an average edge precision of 0.254 which is ranked 5320 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CAND1 | HuMAP2_01882 HuMAP2_03808 |
| ECPAS | HuMAP2_00741 HuMAP2_01358 HuMAP2_01882 HuMAP2_03137 HuMAP2_03992 HuMAP2_06176 |
| CAND2 | HuMAP2_01882 HuMAP2_03118 HuMAP2_03715 HuMAP2_04347 |
| FBXL15 | HuMAP2_00047 HuMAP2_00875 HuMAP2_01504 HuMAP2_01882 HuMAP2_04602 HuMAP2_05397 HuMAP2_05723 |
| CUL1 | HuMAP2_00047 HuMAP2_00875 HuMAP2_01882 HuMAP2_04602 |