hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01887
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MFF | Mitochondrial fission factor | UniProt NCBI |
| FITM2 | Fat storage-inducing transmembrane protein 2 (Fat-inducing protein 2) | UniProt NCBI |
| EDA | Ectodysplasin-A (Ectodermal dysplasia protein) (EDA protein) [Cleaved into: Ectodysplasin-A, membrane form; Ectodysplasin-A, secreted form] | UniProt NCBI |
| ALG5 | Dolichyl-phosphate beta-glucosyltransferase (DolP-glucosyltransferase) (EC 2.4.1.117) (Asparagine-linked glycosylation protein 5 homolog) | UniProt NCBI |
| MGAT5 | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (EC 2.4.1.155) (Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase V) (GlcNAc-T V) (GNT-V) (Mannoside acetylglucosaminyltransferase 5) (N-acetylglucosaminyl-transferase V) [Cleaved into: Secreted alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A (Secreted beta-1,6-N-acetylglucosaminyltransferase V) (Secreted GNT-V)] | UniProt NCBI |
| SPATA19 | Spermatogenesis-associated protein 19, mitochondrial (Spermatogenic cell-specific gene 1 protein) (Spergen-1) | UniProt NCBI |
| CCDC126 | Coiled-coil domain-containing protein 126 | UniProt NCBI |
| GPM6A | Neuronal membrane glycoprotein M6-a (M6a) | UniProt NCBI |
| AP3B2 | AP-3 complex subunit beta-2 (Adaptor protein complex AP-3 subunit beta-2) (Adaptor-related protein complex 3 subunit beta-2) (Beta-3B-adaptin) (Clathrin assembly protein complex 3 beta-2 large chain) (Neuron-specific vesicle coat protein beta-NAP) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00510 | 0.0155091288123 | 0.222222222222 | ALG5 MGAT5 | N-Glycan biosynthesis |
| MIRNA:hsa-miR-5009-5p | 0.0281556835823 | 0.222222222222 | MGAT5 FITM2 | hsa-miR-5009-5p |
| MIRNA:hsa-miR-8058 | 0.0281556835823 | 0.222222222222 | MGAT5 FITM2 | hsa-miR-8058 |
| MIRNA:hsa-miR-1269a | 0.0331335566431 | 0.222222222222 | MGAT5 FITM2 | hsa-miR-1269a |
| MIRNA:hsa-miR-1269b | 0.0357730245743 | 0.222222222222 | MGAT5 FITM2 | hsa-miR-1269b |
| MIRNA:hsa-miR-4529-3p | 0.0357730245743 | 0.222222222222 | MGAT5 FITM2 | hsa-miR-4529-3p |
| CORUM:6629 | 0.0499262710315 | 0.111111111111 | MGAT5 | MAGT5-SLC35A3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCDC126 | GPM6A | 0.328 | 0.517 | bioplex (GPM6A) bioplex_WMM |
| MFF | CCDC126 | 0.091 | 0.355 | bioplex (MFF) bioplex_WMM |
| EDA | GPM6A | 0.089 | 0.355 | bioplex (EDA) bioplex_WMM |
| EDA | AP3B2 | 0.053 | 0.301 | bioplex (EDA) bioplex_WMM |
| MFF | SPATA19 | 0.042 | 0.269 | bioplex (SPATA19) bioplex_WMM |
| MGAT5 | GPM6A | 0.038 | 0.264 | bioplex (GPM6A) bioplex_WMM |
| FITM2 | GPM6A | 0.036 | 0.265 | bioplex (GPM6A) bioplex_WMM |
| EDA | ALG5 | 0.021 | 0.187 | bioplex (EDA) bioplex_WMM |
| MFF | MGAT5 | 0.017 | 0.175 | bioplex (MFF) bioplex_WMM |
| MGAT5 | CCDC126 | 0.008 | 0.09 | bioplex_WMM WMM_only |
| AP3B2 | GPM6A | 0.008 | 0.028 | bioplex_WMM WMM_only |
| CCDC126 | FITM2 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| AP3B2 | ALG5 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| GPM6A | ALG5 | 0.006 | 0.003 | bioplex_WMM WMM_only |
| MGAT5 | ALG5 | 0.006 | 0.012 | bioplex_WMM WMM_only |
| EDA | FITM2 | 0.006 | 0.001 | bioplex_WMM WMM_only |
| EDA | MGAT5 | 0.006 | 0.005 | bioplex_WMM WMM_only |
| MGAT5 | FITM2 | 0.006 | 0.007 | bioplex_WMM WMM_only |
| FITM2 | ALG5 | 0.006 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01887 has an average edge precision of 0.151 which is ranked 6695 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MFF | HuMAP2_01400 HuMAP2_01524 HuMAP2_01887 HuMAP2_05002 |
| FITM2 | HuMAP2_01400 HuMAP2_01887 |
| EDA | HuMAP2_00924 HuMAP2_01887 |
| ALG5 | HuMAP2_01887 |
| MGAT5 | HuMAP2_01400 HuMAP2_01887 |
| SPATA19 | HuMAP2_01400 HuMAP2_01524 HuMAP2_01887 HuMAP2_05002 |
| CCDC126 | HuMAP2_01400 HuMAP2_01524 HuMAP2_01887 HuMAP2_05002 |
| GPM6A | HuMAP2_01400 HuMAP2_01887 HuMAP2_05002 |
| AP3B2 | HuMAP2_00924 HuMAP2_01887 HuMAP2_02783 HuMAP2_05936 HuMAP2_06447 |