hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01891
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FMN1 | Formin-1 (Limb deformity protein homolog) | UniProt NCBI |
| MRM2 | rRNA methyltransferase 2, mitochondrial (EC 2.1.1.-) (16S rRNA (uridine(1369)-2'-O)-methyltransferase) (16S rRNA [Um1369] 2'-O-methyltransferase) (Protein ftsJ homolog 2) | UniProt NCBI |
| MTERF4 | Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (mTERF domain-containing protein 2) [Cleaved into: mTERF domain-containing protein 2 processed] | UniProt NCBI |
| RBFA | Putative ribosome-binding factor A, mitochondrial | UniProt NCBI |
| FLYWCH1 | FLYWCH-type zinc finger-containing protein 1 | UniProt NCBI |
| CYP2S1 | Cytochrome P450 2S1 (EC 1.14.14.-) (CYPIIS1) (Hydroperoxy icosatetraenoate dehydratase) (EC 4.2.1.152) (Thromboxane-A synthase) (EC 5.3.99.5) | UniProt NCBI |
| NUMB | Protein numb homolog (h-Numb) (Protein S171) | UniProt NCBI |
| TEFM | Transcription elongation factor, mitochondrial | UniProt NCBI |
| METTL15 | Probable methyltransferase-like protein 15 (EC 2.1.1.-) (Methyltransferase 5 domain-containing protein 1) | UniProt NCBI |
| KBTBD7 | Kelch repeat and BTB domain-containing protein 7 | UniProt NCBI |
| KBTBD6 | Kelch repeat and BTB domain-containing protein 6 | UniProt NCBI |
| DOK4 | Docking protein 4 (Downstream of tyrosine kinase 4) (Insulin receptor substrate 5) (IRS-5) (IRS5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6793080 | 0.00215225370556 | 0.166666666667 | MRM2 MTERF4 | rRNA modification in the mitochondrion |
| REAC:R-HSA-8868766 | 0.00644520730531 | 0.166666666667 | MRM2 MTERF4 | rRNA processing in the mitochondrion |
| GO:0031167 | 0.0226023794314 | 0.25 | METTL15 MRM2 MTERF4 | rRNA methylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KBTBD6 | KBTBD7 | 1.0 | 0.949 | hein_WMM bioplex (KBTBD7) bioplex_WMM youn_WMM hein (KBTBD7) gupta_WMM boldt_WMM |
| KBTBD7 | TEFM | 0.99 | 0.909 | hein_WMM bioplex (KBTBD7) bioplex_WMM hein (KBTBD7) |
| KBTBD7 | CYP2S1 | 0.288 | 0.489 | bioplex (KBTBD7) bioplex_WMM |
| KBTBD7 | DOK4 | 0.106 | 0.372 | bioplex (DOK4) bioplex_WMM |
| KBTBD7 | RBFA | 0.101 | 0.364 | bioplex (KBTBD7,RBFA) bioplex_WMM |
| RBFA | METTL15 | 0.096 | 0.358 | bioplex (RBFA) bioplex_WMM |
| MRM2 | KBTBD7 | 0.094 | 0.357 | bioplex (KBTBD7) bioplex_WMM |
| FLYWCH1 | KBTBD7 | 0.084 | 0.347 | bioplex (KBTBD7) bioplex_WMM |
| KBTBD6 | DOK4 | 0.072 | 0.353 | bioplex (DOK4) bioplex_WMM |
| CYP2S1 | FMN1 | 0.046 | 0.292 | bioplex (FMN1) bioplex_WMM |
| KBTBD7 | MTERF4 | 0.042 | 0.269 | bioplex (KBTBD7) bioplex_WMM |
| KBTBD7 | NUMB | 0.029 | 0.233 | bioplex (KBTBD7) bioplex_WMM youn_WMM |
| FLYWCH1 | TEFM | 0.008 | 0.085 | bioplex_WMM WMM_only |
| MRM2 | MTERF4 | 0.008 | 0.083 | bioplex_WMM WMM_only |
| FLYWCH1 | MTERF4 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| FLYWCH1 | RBFA | 0.008 | 0.067 | bioplex_WMM WMM_only |
| FLYWCH1 | CYP2S1 | 0.008 | 0.065 | bioplex_WMM WMM_only |
| FLYWCH1 | NUMB | 0.008 | 0.066 | bioplex_WMM WMM_only |
| FLYWCH1 | MRM2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| KBTBD6 | TEFM | 0.008 | 0.04 | hein_WMM bioplex_WMM WMM_only |
| FLYWCH1 | METTL15 | 0.008 | 0.02 | bioplex_WMM WMM_only |
| TEFM | MTERF4 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| MRM2 | TEFM | 0.008 | 0.024 | bioplex_WMM youn_WMM WMM_only |
| TEFM | RBFA | 0.008 | 0.011 | bioplex_WMM WMM_only |
| TEFM | CYP2S1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| TEFM | NUMB | 0.007 | 0.005 | bioplex_WMM WMM_only |
| RBFA | MTERF4 | 0.007 | 0.01 | bioplex_WMM WMM_only |
| CYP2S1 | MTERF4 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| MTERF4 | NUMB | 0.007 | 0.005 | bioplex_WMM WMM_only |
| RBFA | CYP2S1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| RBFA | NUMB | 0.007 | 0.003 | bioplex_WMM WMM_only |
| TEFM | METTL15 | 0.007 | 0.012 | bioplex_WMM youn_WMM WMM_only |
| KBTBD6 | FLYWCH1 | 0.007 | 0.009 | bioplex_WMM WMM_only |
| CYP2S1 | NUMB | 0.007 | 0.009 | bioplex_WMM WMM_only |
| MRM2 | RBFA | 0.007 | 0.004 | bioplex_WMM WMM_only |
| KBTBD6 | NUMB | 0.007 | 0.002 | bioplex_WMM boldt boldt_WMM |
| MRM2 | CYP2S1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| MRM2 | NUMB | 0.007 | 0.005 | bioplex_WMM WMM_only |
| METTL15 | MTERF4 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| MRM2 | METTL15 | 0.007 | 0.005 | bioplex_WMM youn_WMM WMM_only |
| METTL15 | CYP2S1 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| METTL15 | NUMB | 0.007 | 0.004 | bioplex_WMM WMM_only |
| KBTBD6 | MTERF4 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| KBTBD6 | CYP2S1 | 0.007 | 0.005 | bioplex_WMM WMM_only |
| KBTBD6 | MRM2 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| KBTBD6 | METTL15 | 0.006 | 0.005 | bioplex_WMM WMM_only |
| KBTBD6 | RBFA | 0.005 | 0.009 | bioplex (RBFA) bioplex_WMM |
| KBTBD7 | METTL15 | 0.004 | 0.013 | bioplex (KBTBD7) bioplex_WMM |
Images
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Complex HuMAP2_01891 has an average edge precision of 0.126 which is ranked 6849 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FMN1 | HuMAP2_01595 HuMAP2_01891 |
| MRM2 | HuMAP2_01025 HuMAP2_01870 HuMAP2_01891 |
| MTERF4 | HuMAP2_01891 HuMAP2_03597 HuMAP2_04459 |
| RBFA | HuMAP2_01581 HuMAP2_01776 HuMAP2_01891 HuMAP2_05881 |
| FLYWCH1 | HuMAP2_01025 HuMAP2_01891 |
| CYP2S1 | HuMAP2_01595 HuMAP2_01891 |
| NUMB | HuMAP2_01891 HuMAP2_03989 HuMAP2_06613 |
| TEFM | HuMAP2_01025 HuMAP2_01891 HuMAP2_03158 HuMAP2_06041 |
| METTL15 | HuMAP2_01581 HuMAP2_01776 HuMAP2_01891 HuMAP2_05881 |
| KBTBD7 | HuMAP2_01025 HuMAP2_01891 HuMAP2_03158 HuMAP2_06041 |
| KBTBD6 | HuMAP2_00866 HuMAP2_01025 HuMAP2_01891 HuMAP2_03890 HuMAP2_05857 HuMAP2_06041 |
| DOK4 | HuMAP2_01025 HuMAP2_01891 HuMAP2_05857 |