hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01936
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WASF3 | Wiskott-Aldrich syndrome protein family member 3 (WASP family protein member 3) (Protein WAVE-3) (Verprolin homology domain-containing protein 3) | UniProt NCBI |
| CYFIP2 | Cytoplasmic FMR1-interacting protein 2 (p53-inducible protein 121) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5663213 | 0.000997174460113 | 1.0 | CYFIP2 WASF3 | RHO GTPases Activate WASPs and WAVEs |
| KEGG:05130 | 0.00227250014745 | 1.0 | CYFIP2 WASF3 | Pathogenic Escherichia coli infection |
| REAC:R-HSA-2029482 | 0.00286750504412 | 1.0 | CYFIP2 WASF3 | Regulation of actin dynamics for phagocytic cup formation |
| REAC:R-HSA-2029480 | 0.0052959181411 | 1.0 | CYFIP2 WASF3 | Fcgamma receptor (FCGR) dependent phagocytosis |
| REAC:R-HSA-4420097 | 0.00686290657842 | 1.0 | CYFIP2 WASF3 | VEGFA-VEGFR2 Pathway |
| REAC:R-HSA-194138 | 0.00812990471598 | 1.0 | CYFIP2 WASF3 | Signaling by VEGF |
| CORUM:7561 | 0.0499173803268 | 0.5 | WASF3 | NCKAP1-WASF3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| WASF3 | CYFIP2 | 0.982 | 0.898 | bioplex (WASF3) bioplex_WMM Guru Malo fraction |
Images
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Complex HuMAP2_01936 has an average edge precision of 0.898 which is ranked 580 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| WASF3 | HuMAP2_00378 HuMAP2_01936 HuMAP2_06838 |
| CYFIP2 | HuMAP2_00378 HuMAP2_01936 HuMAP2_06838 |