hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01943
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CCAR2 | Cell cycle and apoptosis regulator protein 2 (Cell division cycle and apoptosis regulator protein 2) (DBIRD complex subunit KIAA1967) (Deleted in breast cancer gene 1 protein) (DBC-1) (DBC.1) (NET35) (p30 DBC) | UniProt NCBI |
| LMNA | Prelamin-A/C [Cleaved into: Lamin-A/C (70 kDa lamin) (Renal carcinoma antigen NY-REN-32)] | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4299 | 0.0166454435758 | 0.5 | LMNA | Lamin A-processing pathway |
| HP:0000287 | 0.0497341708567 | 0.5 | LMNA | Increased facial adipose tissue |
| HP:0008739 | 0.0497341708567 | 0.5 | LMNA | Labial pseudohypertrophy |
| HP:0008985 | 0.0497341708567 | 0.5 | LMNA | Increased intramuscular fat |
| HP:0010330 | 0.0497341708567 | 0.5 | LMNA | Abnormality of the phalanges of the 3rd toe |
| HP:0010359 | 0.0497341708567 | 0.5 | LMNA | Aplasia/Hypoplasia of the phalanges of the 3rd toe |
| HP:0012645 | 0.0497341708567 | 0.5 | LMNA | Enlarged peripheral nerve |
| HP:0012723 | 0.0497341708567 | 0.5 | LMNA | Sinoatrial block |
| HP:0100362 | 0.0497341708567 | 0.5 | LMNA | Aplasia of the phalanges of the 3rd toe |
| CORUM:6091 | 0.0499173803268 | 0.5 | LMNA | NF-YA-LaminA complex |
| CORUM:6846 | 0.0499173803268 | 0.5 | CCAR2 | DBC1-SIRT1 complex |
| CORUM:6847 | 0.0499173803268 | 0.5 | CCAR2 | DBIRD complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LMNA | CCAR2 | 0.026 | 0.221 | bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_01943 has an average edge precision of 0.221 which is ranked 5840 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CCAR2 | HuMAP2_01870 HuMAP2_01943 HuMAP2_02571 |
| LMNA | HuMAP2_01147 HuMAP2_01943 HuMAP2_06899 |