hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01944
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NAXD | ATP-dependent (S)-NAD(P)H-hydrate dehydratase (EC 4.2.1.93) (ATP-dependent NAD(P)HX dehydratase) (Carbohydrate kinase domain-containing protein) (NAD(P)HX dehydratase) | UniProt NCBI |
| TRAP1 | Heat shock protein 75 kDa, mitochondrial (HSP 75) (TNFR-associated protein 1) (Tumor necrosis factor type 1 receptor-associated protein) (TRAP-1) | UniProt NCBI |
| ACSF3 | Acyl-CoA synthetase family member 3, mitochondrial (EC 6.2.1.-) | UniProt NCBI |
| ANXA4 | Annexin A4 (35-beta calcimedin) (Annexin IV) (Annexin-4) (Carbohydrate-binding protein p33/p41) (Chromobindin-4) (Endonexin I) (Lipocortin IV) (P32.5) (PP4-X) (Placental anticoagulant protein II) (PAP-II) (Protein II) | UniProt NCBI |
| PNP | Purine nucleoside phosphorylase (PNP) (EC 2.4.2.1) (Inosine phosphorylase) (Inosine-guanosine phosphorylase) | UniProt NCBI |
| ECHS1 | Enoyl-CoA hydratase, mitochondrial (EC 4.2.1.17) (Enoyl-CoA hydratase 1) (Short-chain enoyl-CoA hydratase) (SCEH) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00280 | 0.00671425203226 | 0.333333333333 | ECHS1 ACSF3 | Valine, leucine and isoleucine degradation |
| KEGG:01212 | 0.00854975942062 | 0.333333333333 | ECHS1 ACSF3 | Fatty acid metabolism |
| CORUM:6208 | 0.0249904952816 | 0.166666666667 | PNP | PNP homotrimer complex |
| REAC:R-HSA-1430728 | 0.0278608311428 | 0.833333333333 | ECHS1 PNP ACSF3 NAXD TRAP1 | Metabolism |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ECHS1 | PNP | 0.447 | 0.592 | bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| TRAP1 | ACSF3 | 0.162 | 0.42 | bioplex (ACSF3) bioplex_WMM fraction |
| ECHS1 | TRAP1 | 0.146 | 0.409 | bioplex (ECHS1) bioplex_WMM Guru boldt fraction boldt_WMM |
| TRAP1 | PNP | 0.116 | 0.387 | bioplex_WMM boldt fraction boldt_WMM |
| ECHS1 | ANXA4 | 0.06 | 0.336 | bioplex_WMM fraction treiber_WMM |
| TRAP1 | NAXD | 0.04 | 0.268 | bioplex (NAXD) fraction |
| ECHS1 | ACSF3 | 0.007 | 0.0 | bioplex_WMM WMM_only |
| TRAP1 | ANXA4 | 0.006 | 0.003 | bioplex (ANXA4) bioplex_WMM |
| ANXA4 | PNP | 0.006 | 0.003 | bioplex (ANXA4) bioplex_WMM treiber_WMM |
| NAXD | PNP | 0.006 | 0.004 | bioplex (NAXD) |
| ECHS1 | NAXD | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_01944 has an average edge precision of 0.22 which is ranked 5849 out of all 6965 complexes.
Related Complexes