hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01953
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DCAF1 | DDB1- and CUL4-associated factor 1 (HIV-1 Vpr-binding protein) (VprBP) (Serine/threonine-protein kinase VPRBP) (EC 2.7.11.1) (Vpr-interacting protein) | UniProt NCBI |
| DDA1 | DET1- and DDB1-associated protein 1 (Placenta cross-immune reaction antigen 1) (PCIA-1) | UniProt NCBI |
| AMBRA1 | Activating molecule in BECN1-regulated autophagy protein 1 | UniProt NCBI |
| CISH | Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Protein G18) (Suppressor of cytokine signaling) (SOCS) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6861-5p | 0.0281535250235 | 0.5 | AMBRA1 DDA1 | hsa-miR-6861-5p |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DCAF1 | DDA1 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt hein (DDA1) Malo fraction boldt_WMM |
| DDA1 | AMBRA1 | 0.393 | 0.556 | hein_WMM bioplex_WMM boldt hein (AMBRA1,DDA1) boldt_WMM |
| AMBRA1 | CISH | 0.037 | 0.266 | bioplex (CISH) bioplex_WMM |
| DCAF1 | AMBRA1 | 0.006 | 0.001 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_01953 has an average edge precision of 0.443 which is ranked 2919 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DCAF1 | HuMAP2_01953 HuMAP2_02235 HuMAP2_06545 |
| DDA1 | HuMAP2_01953 HuMAP2_02235 HuMAP2_06545 |
| AMBRA1 | HuMAP2_01953 HuMAP2_05665 |
| CISH | HuMAP2_01953 |