hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01958
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| B9D1 | B9 domain-containing protein 1 (MKS1-related protein 1) | UniProt NCBI |
| B9D2 | B9 domain-containing protein 2 (MKS1-related protein 2) | UniProt NCBI |
| TMEM231 | Transmembrane protein 231 | UniProt NCBI |
| MKS1 | Meckel syndrome type 1 protein | UniProt NCBI |
| UGCG | Ceramide glucosyltransferase (EC 2.4.1.80) (GLCT-1) (Glucosylceramide synthase) (GCS) (UDP-glucose ceramide glucosyltransferase) (UDP-glucose:N-acylsphingosine D-glucosyltransferase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0006870 | 2.28718019524e-09 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Lobar holoprosencephaly |
| HP:0010459 | 2.28718019524e-09 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | True hermaphroditism |
| HP:0100732 | 6.0873653933e-09 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Pancreatic fibrosis |
| HP:0000068 | 9.18973970649e-09 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Urethral atresia |
| HP:0001737 | 1.33478702661e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Pancreatic cysts |
| HP:0001747 | 1.58894670824e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Accessory spleen |
| HP:0002085 | 1.87774510411e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Occipital encephalocele |
| HP:0006706 | 3.44137340076e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cystic liver disease |
| HP:0010295 | 3.95099391241e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the tongue |
| HP:0000073 | 4.51517866018e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Ureteral duplication |
| HP:0000221 | 5.13768545876e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Furrowed tongue |
| HP:0002419 | 5.82239685971e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Molar tooth sign on MRI |
| HP:0000647 | 6.5733201177e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Sclerocornea |
| HP:0009799 | 7.39458715673e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Supernumerary spleens |
| HP:0000037 | 7.39458715673e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Male pseudohermaphroditism |
| GO:0036038 | 8.71719597884e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | MKS complex |
| WP:WP4656 | 9.79793498057e-08 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Joubert Syndrome |
| HP:0002612 | 1.40464963576e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Congenital hepatic fibrosis |
| HP:0001830 | 1.869489595e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Postaxial foot polydactyly |
| HP:0001177 | 2.44106529439e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Preaxial hand polydactyly |
| HP:0002418 | 3.13456500912e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of midbrain morphology |
| HP:0001360 | 3.96618300513e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Holoprosencephaly |
| HP:0000528 | 4.27702575743e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Anophthalmia |
| HP:0002323 | 5.31972975444e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Anencephaly |
| HP:0010322 | 7.46676196203e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the 5th toe |
| HP:0001746 | 8.48589656291e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Asplenia |
| HP:0012090 | 8.48589656291e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal pancreas morphology |
| HP:0010451 | 9.03288682556e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the spleen |
| HP:0100258 | 9.60588559795e-07 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Preaxial polydactyly |
| HP:0002084 | 2.53509281246e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Encephalocele |
| HP:0011815 | 2.53509281246e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cephalocele |
| HP:0001162 | 2.78658791667e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Postaxial hand polydactyly |
| HP:0001696 | 2.91912503153e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Situs inversus totalis |
| HP:0011534 | 3.0563306594e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal spatial orientation of the cardiac segments |
| HP:0000293 | 3.34518123836e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Full cheeks |
| HP:0000062 | 3.4970461515e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Ambiguous genitalia |
| HP:0001562 | 3.98374493402e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Oligohydramnios |
| HP:0000003 | 3.98374493402e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Multicystic kidney dysplasia |
| HP:0008053 | 4.15672679627e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the iris |
| HP:0008055 | 4.15672679627e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia affecting the uvea |
| HP:0001829 | 4.33527665196e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Foot polydactyly |
| HP:0025633 | 4.70955338699e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal ureter morphology |
| HP:0001395 | 4.70955338699e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Hepatic fibrosis |
| HP:0001651 | 4.70955338699e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Dextrocardia |
| HP:0004307 | 4.90551985117e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal anatomic location of the heart |
| HP:0008062 | 4.90551985117e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia affecting the anterior segment of the eye |
| HP:0009136 | 5.10753347779e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Duplication involving bones of the feet |
| HP:0000457 | 5.53019485882e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Depressed nasal ridge |
| HP:0001305 | 6.45357114333e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Dandy-Walker malformation |
| HP:0005445 | 6.70142334533e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Widened posterior fossa |
| HP:0000532 | 7.21845313622e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal chorioretinal morphology |
| HP:0000482 | 7.48789722069e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Microcornea |
| HP:0002198 | 8.64170091152e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Dilated fourth ventricle |
| HP:0010950 | 8.64170091152e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the fourth ventricle |
| HP:0002350 | 8.94984932436e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cerebellar cyst |
| HP:0100259 | 8.94984932436e-06 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Postaxial polydactyly |
| HP:0000932 | 1.0615850525e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the posterior cranial fossa |
| HP:0002693 | 1.41871310941e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the skull base |
| HP:0000610 | 1.6523212534e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal choroid morphology |
| HP:0001120 | 1.6523212534e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of corneal size |
| HP:0000340 | 1.7534015744e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Sloping forehead |
| HP:0030724 | 1.91361836079e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Central nervous system cyst |
| HP:0010576 | 1.91361836079e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Intracranial cystic lesion |
| HP:0001161 | 2.66642116579e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Hand polydactyly |
| GO:0035869 | 2.802206198e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | ciliary transition zone |
| HP:0004426 | 3.19701351784e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cheek |
| HP:0001320 | 3.53362419786e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cerebellar vermis hypoplasia |
| HP:0009997 | 4.5965589507e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Duplication of phalanx of hand |
| HP:0004275 | 4.70382573008e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Duplication of hand bones |
| HP:0009142 | 4.70382573008e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Duplication of bones involving the upper extremities |
| HP:0011119 | 5.26854162891e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the nasal dorsum |
| HP:0006817 | 5.7556748482e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the cerebellar vermis |
| HP:0007957 | 6.27577332437e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Corneal opacity |
| HP:0006487 | 6.68835069866e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Bowing of the long bones |
| HP:0000368 | 7.26964164372e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Low-set, posteriorly rotated ears |
| HP:0006504 | 7.26964164372e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Anomaly of the limb diaphyses |
| HP:0000568 | 7.88795412529e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Microphthalmia |
| HP:0010442 | 8.21147108818e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Polydactyly |
| HP:0000107 | 9.24180330345e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Renal cyst |
| HP:0007700 | 9.42250327682e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Ocular anterior segment dysgenesis |
| HP:0002334 | 9.42250327682e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cerebellar vermis |
| HP:0030809 | 9.98049598929e-05 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal tongue morphology |
| HP:0000940 | 0.000107625221209 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal diaphysis morphology |
| HP:0001732 | 0.000115895357239 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the pancreas |
| WP:WP4536 | 0.000117777755844 | 0.6 | B9D1 TMEM231 MKS1 | Genes related to primary cilium development (based on CRISPR) |
| HP:0100887 | 0.000118035151383 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of globe size |
| HP:0000069 | 0.00014109649389 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the ureter |
| HP:0002438 | 0.000223698618662 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cerebellar malformation |
| HP:0000157 | 0.000227195240448 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the tongue |
| HP:0001560 | 0.000227195240448 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the amniotic fluid |
| HP:0001172 | 0.000230732596549 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal thumb morphology |
| HP:0004422 | 0.000318556115604 | 0.6 | B9D1 TMEM231 MKS1 | Biparietal narrowing |
| HP:0000238 | 0.000338051691633 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Hydrocephalus |
| REAC:R-HSA-5620912 | 0.000372887468142 | 0.6 | B9D1 B9D2 MKS1 | Anchoring of the basal body to the plasma membrane |
| HP:0000795 | 0.000398537766623 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the urethra |
| HP:0000358 | 0.00040391961752 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Posteriorly rotated ears |
| HP:0001883 | 0.000454837491475 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Talipes |
| HP:0005656 | 0.000472831071609 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Positional foot deformity |
| HP:0004207 | 0.000523418462205 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal 5th finger morphology |
| HP:0008056 | 0.000550178155431 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia affecting the eye |
| HP:0000525 | 0.000563935221561 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality iris morphology |
| HP:0000657 | 0.000602597659635 | 0.6 | B9D1 TMEM231 MKS1 | Oculomotor apraxia |
| HP:0025408 | 0.00114507726185 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal spleen morphology |
| HP:0002921 | 0.00118085147505 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cerebrospinal fluid |
| HP:0002789 | 0.00128396303463 | 0.6 | B9D1 TMEM231 MKS1 | Tachypnea |
| HP:0004362 | 0.00136740386969 | 0.6 | B9D1 TMEM231 MKS1 | Abnormality of enteric ganglion morphology |
| HP:0012331 | 0.00136740386969 | 0.6 | B9D1 TMEM231 MKS1 | Abnormal autonomic nervous system morphology |
| HP:0002251 | 0.00136740386969 | 0.6 | B9D1 TMEM231 MKS1 | Aganglionic megacolon |
| HP:0025028 | 0.00136740386969 | 0.6 | B9D1 TMEM231 MKS1 | Abnormality of enteric nervous system morphology |
| HP:0000553 | 0.0013724055692 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal uvea morphology |
| HP:0001743 | 0.0013724055692 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the spleen |
| HP:0000309 | 0.00151240558538 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the midface |
| HP:0000175 | 0.00172599547261 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cleft palate |
| HP:0100737 | 0.00174206825411 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal hard palate morphology |
| HP:0002553 | 0.00228570439764 | 0.6 | B9D1 TMEM231 MKS1 | Highly arched eyebrow |
| HP:0000202 | 0.00235830272854 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Oral cleft |
| HP:0000648 | 0.00244023376223 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Optic atrophy |
| HP:0002119 | 0.00272124462781 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Ventriculomegaly |
| HP:0001780 | 0.00278938291813 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of toe |
| HP:0011314 | 0.00300145409113 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of long bone morphology |
| REAC:R-HSA-5617833 | 0.00304975168622 | 0.6 | B9D1 B9D2 MKS1 | Cilium Assembly |
| HP:0100763 | 0.0031998636837 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the lymphatic system |
| HP:0002186 | 0.00330690735156 | 0.6 | B9D1 TMEM231 MKS1 | Apraxia |
| HP:0005918 | 0.00335497414372 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal finger phalanx morphology |
| HP:0040069 | 0.00343460048625 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal lower limb bone morphology |
| HP:0000508 | 0.00357043490873 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Ptosis |
| HP:0000180 | 0.00361982515692 | 0.4 | MKS1 TMEM231 | Lobulated tongue |
| HP:0000612 | 0.00362270778764 | 0.6 | B9D1 TMEM231 MKS1 | Iris coloboma |
| HP:0000316 | 0.00373868304213 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Hypertelorism |
| HP:0012795 | 0.00376728934267 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the optic disc |
| HP:0000481 | 0.00376728934267 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal cornea morphology |
| HP:0000369 | 0.00391277858584 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Low-set ears |
| HP:0007370 | 0.00403215607607 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the corpus callosum |
| HP:0000028 | 0.00406242032099 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cryptorchidism |
| HP:0000347 | 0.00427904215876 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Micrognathia |
| HP:0009118 | 0.00437447096145 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia of the mandible |
| HP:0010936 | 0.00457008280214 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the lower urinary tract |
| HP:0009116 | 0.00467030011526 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/Hypoplasia involving bones of the skull |
| HP:0000357 | 0.00494556523319 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal location of ears |
| HP:0000518 | 0.0050162319589 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Cataract |
| HP:0001273 | 0.00564773325088 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal corpus callosum morphology |
| HP:0000517 | 0.00564773325088 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the lens |
| HP:0000426 | 0.00629008671885 | 0.6 | B9D1 TMEM231 MKS1 | Prominent nasal bridge |
| HP:0000276 | 0.0066485644099 | 0.6 | B9D1 TMEM231 MKS1 | Long face |
| HP:0002118 | 0.00708652002063 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cerebral ventricles |
| HP:0002648 | 0.00708652002063 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of calvarial morphology |
| HP:0000587 | 0.00717888856225 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the optic nerve |
| HP:0009122 | 0.00731912076265 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/hypoplasia affecting bones of the axial skeleton |
| HP:0001197 | 0.0079005654453 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of prenatal development or birth |
| HP:0001317 | 0.0083587342088 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal cerebellum morphology |
| HP:0011283 | 0.00856859850873 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the metencephalon |
| HP:0011282 | 0.00856859850873 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of hindbrain morphology |
| HP:0000589 | 0.00864502491522 | 0.6 | B9D1 TMEM231 MKS1 | Coloboma |
| HP:0410042 | 0.00889072727396 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal liver morphology |
| HP:0002270 | 0.0089379069678 | 0.6 | B9D1 TMEM231 MKS1 | Abnormality of the autonomic nervous system |
| HP:0410008 | 0.00923728902624 | 0.6 | B9D1 TMEM231 MKS1 | Abnormality of the peripheral nervous system |
| HP:0100729 | 0.00938943928499 | 0.6 | B9D1 TMEM231 MKS1 | Large face |
| REAC:R-HSA-1852241 | 0.00946786790116 | 0.6 | B9D1 B9D2 MKS1 | Organelle biogenesis and maintenance |
| HP:0002500 | 0.00997055798897 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cerebral white matter |
| HP:0000479 | 0.0103310114373 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal retinal morphology |
| HP:0000277 | 0.0106387322837 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the mandible |
| HP:0000035 | 0.0107010867528 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal testis morphology |
| HP:0010938 | 0.0110169532253 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the external nose |
| HP:0100886 | 0.0113397146668 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of globe location |
| HP:0002104 | 0.0124188738287 | 0.6 | B9D1 TMEM231 MKS1 | Apnea |
| HP:0000290 | 0.0126308245049 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the forehead |
| HP:0002683 | 0.0128442724502 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the calvaria |
| HP:0030791 | 0.012988055981 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal jaw morphology |
| HP:0012210 | 0.0136499696929 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal renal morphology |
| HP:0010993 | 0.0154556290894 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the cerebral subcortex |
| HP:0000174 | 0.0162084757532 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal palate morphology |
| HP:0000032 | 0.0201885758558 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of male external genitalia |
| HP:0001392 | 0.0201885758558 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the liver |
| HP:0002876 | 0.0215275853758 | 0.4 | B9D1 MKS1 | Episodic tachypnea |
| HP:0001167 | 0.0227034392536 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of finger |
| HP:0010461 | 0.0230334244903 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the male genitalia |
| HP:0000811 | 0.0231442083502 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal external genitalia |
| HP:0009115 | 0.0234789391763 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Aplasia/hypoplasia involving the skeleton |
| HP:0000356 | 0.0239308330272 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the outer ear |
| HP:0011821 | 0.0258033904131 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of facial skeleton |
| HP:0000864 | 0.0264139121191 | 0.6 | B9D1 TMEM231 MKS1 | Abnormality of the hypothalamus-pituitary axis |
| HP:0000113 | 0.0325153883173 | 0.4 | MKS1 TMEM231 | Polycystic kidney dysplasia |
| HP:0000252 | 0.0326474959437 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Microcephaly |
| HP:0040195 | 0.0332246010255 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Decreased head circumference |
| HP:0004328 | 0.0371626603223 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal anterior eye segment morphology |
| HP:0001098 | 0.0377979531188 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal fundus morphology |
| HP:0004329 | 0.0382796920379 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal posterior eye segment morphology |
| HP:0002793 | 0.0384968933304 | 0.6 | B9D1 TMEM231 MKS1 | Abnormal pattern of respiration |
| HP:0002012 | 0.038603375935 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the abdominal organs |
| HP:0000077 | 0.0399184873082 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the kidney |
| HP:0010935 | 0.0446037445864 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the upper urinary tract |
| HP:0001760 | 0.0458823387011 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormality of the foot |
| HP:0001627 | 0.047946296424 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal heart morphology |
| HP:0011297 | 0.0494900867638 | 0.8 | B9D1 TMEM231 B9D2 MKS1 | Abnormal digit morphology |
| CORUM:6682 | 0.0499494897235 | 0.2 | MKS1 | MKS1-TMEM67 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| B9D1 | TMEM231 | 0.235 | 0.47 | bioplex (TMEM231) bioplex_WMM boldt boldt_WMM |
| B9D1 | B9D2 | 0.222 | 0.466 | bioplex_WMM gupta (B9D2) boldt (B9D2) gupta_WMM boldt_WMM |
| B9D1 | MKS1 | 0.217 | 0.465 | bioplex_WMM gupta (MKS1) boldt gupta_WMM boldt_WMM |
| MKS1 | B9D2 | 0.066 | 0.349 | bioplex_WMM gupta (B9D2,MKS1) boldt (B9D2) gupta_WMM boldt_WMM |
| B9D2 | TMEM231 | 0.054 | 0.298 | bioplex (TMEM231) bioplex_WMM boldt (B9D2) boldt_WMM |
| UGCG | TMEM231 | 0.038 | 0.264 | bioplex (TMEM231) bioplex_WMM |
| UGCG | B9D2 | 0.008 | 0.065 | bioplex_WMM WMM_only |
| UGCG | B9D1 | 0.008 | 0.028 | bioplex_WMM WMM_only |
| UGCG | MKS1 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| MKS1 | TMEM231 | 0.0 | 0.002 | bioplex (TMEM231) bioplex_WMM boldt boldt_WMM |
Images
Click to enlarge
Complex HuMAP2_01958 has an average edge precision of 0.241 which is ranked 5504 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| B9D1 | HuMAP2_01958 HuMAP2_04399 |
| B9D2 | HuMAP2_01958 HuMAP2_04399 |
| TMEM231 | HuMAP2_01958 HuMAP2_04399 |
| MKS1 | HuMAP2_01958 HuMAP2_04399 |
| UGCG | HuMAP2_00418 HuMAP2_01958 HuMAP2_02134 HuMAP2_04236 HuMAP2_04304 HuMAP2_06332 |