hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_01959
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IGBP1 | Immunoglobulin-binding protein 1 (B-cell signal transduction molecule alpha 4) (Protein alpha-4) (CD79a-binding protein 1) (Protein phosphatase 2/4/6 regulatory subunit) (Renal carcinoma antigen NY-REN-16) | UniProt NCBI |
| FBP1 | Fructose-1,6-bisphosphatase 1 (FBPase 1) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Liver FBPase) | UniProt NCBI |
| TTR | Transthyretin (ATTR) (Prealbumin) (TBPA) | UniProt NCBI |
| HMGCS1 | Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMG-CoA synthase) (EC 2.3.3.10) (3-hydroxy-3-methylglutaryl coenzyme A synthase) | UniProt NCBI |
| ST6GALNAC5 | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 (EC 2.4.99.-) (GD1 alpha synthase) (GalNAc alpha-2,6-sialyltransferase V) (ST6GalNAc V) (ST6GalNAcV) (Sialyltransferase 7E) (SIAT7-E) | UniProt NCBI |
| FBP2 | Fructose-1,6-bisphosphatase isozyme 2 (FBPase 2) (EC 3.1.3.11) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 2) (Muscle FBPase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0009312 | 0.000824951429902 | 0.5 | FBP1 FBP2 ST6GALNAC5 | oligosaccharide biosynthetic process |
| KEGG:00030 | 0.0025298764655 | 0.333333333333 | FBP1 FBP2 | Pentose phosphate pathway |
| KEGG:00051 | 0.0032877278217 | 0.333333333333 | FBP1 FBP2 | Fructose and mannose metabolism |
| WP:WP534 | 0.00524729006009 | 0.333333333333 | FBP1 FBP2 | Glycolysis and Gluconeogenesis |
| GO:0042132 | 0.00676235117068 | 0.333333333333 | FBP1 FBP2 | fructose 1,6-bisphosphate 1-phosphatase activity |
| GO:0005986 | 0.00676235117068 | 0.333333333333 | FBP1 FBP2 | sucrose biosynthetic process |
| REAC:R-HSA-70263 | 0.00959640616298 | 0.333333333333 | FBP1 FBP2 | Gluconeogenesis |
| GO:0009311 | 0.0118307664632 | 0.5 | FBP1 FBP2 ST6GALNAC5 | oligosaccharide metabolic process |
| KEGG:00010 | 0.0120956152943 | 0.333333333333 | FBP1 FBP2 | Glycolysis / Gluconeogenesis |
| GO:0005985 | 0.020283420769 | 0.333333333333 | FBP1 FBP2 | sucrose metabolic process |
| KEGG:04922 | 0.0280749165362 | 0.333333333333 | FBP1 FBP2 | Glucagon signaling pathway |
| KEGG:01100 | 0.0331288091988 | 0.666666666667 | FBP1 ST6GALNAC5 FBP2 HMGCS1 | Metabolic pathways |
| KEGG:04152 | 0.0381607333212 | 0.333333333333 | FBP1 FBP2 | AMPK signaling pathway |
| KEGG:01200 | 0.039527830217 | 0.333333333333 | FBP1 FBP2 | Carbon metabolism |
| KEGG:04910 | 0.0474671394747 | 0.333333333333 | FBP1 FBP2 | Insulin signaling pathway |
| CORUM:6821 | 0.0499726005494 | 0.166666666667 | TTR | TTR-RBP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FBP1 | FBP2 | 0.999 | 0.946 | bioplex (FBP1,FBP2) bioplex_WMM |
| FBP1 | ST6GALNAC5 | 0.037 | 0.267 | bioplex (ST6GALNAC5) bioplex_WMM |
| HMGCS1 | FBP1 | 0.028 | 0.232 | fraction |
| HMGCS1 | TTR | 0.025 | 0.211 | fraction |
| HMGCS1 | IGBP1 | 0.024 | 0.215 | Guru fraction |
| IGBP1 | FBP1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| IGBP1 | ST6GALNAC5 | 0.006 | 0.007 | bioplex (ST6GALNAC5) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_01959 has an average edge precision of 0.268 which is ranked 5060 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IGBP1 | HuMAP2_01959 HuMAP2_02007 |
| FBP1 | HuMAP2_01959 HuMAP2_04844 HuMAP2_05148 HuMAP2_06742 |
| TTR | HuMAP2_01959 HuMAP2_04253 |
| HMGCS1 | HuMAP2_00292 HuMAP2_01959 HuMAP2_04726 HuMAP2_05645 |
| ST6GALNAC5 | HuMAP2_01959 HuMAP2_05148 |
| FBP2 | HuMAP2_01959 HuMAP2_04844 HuMAP2_05148 HuMAP2_06742 |