hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01966
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GIPC1 | PDZ domain-containing protein GIPC1 (GAIP C-terminus-interacting protein) (RGS-GAIP-interacting protein) (RGS19-interacting protein 1) (Synectin) (Tax interaction protein 2) (TIP-2) | UniProt NCBI |
| MMUT | Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase) | UniProt NCBI |
| APIP | Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase) (EC 4.2.1.109) (APAF1-interacting protein) (hAPIP) | UniProt NCBI |
| KYNU | Kynureninase (EC 3.7.1.3) (L-kynurenine hydrolase) | UniProt NCBI |
| CS | Citrate synthase, mitochondrial (EC 2.3.3.1) (Citrate (Si)-synthase) | UniProt NCBI |
| RAD23B | UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00630 | 0.00271009618492 | 0.333333333333 | CS MMUT | Glyoxylate and dicarboxylate metabolism |
| WP:WP3925 | 0.021066272601 | 0.333333333333 | CS MMUT | Amino Acid metabolism |
| KEGG:01100 | 0.0331288091988 | 0.666666666667 | KYNU MMUT APIP CS | Metabolic pathways |
| KEGG:01200 | 0.039527830217 | 0.333333333333 | CS MMUT | Carbon metabolism |
| CORUM:2486 | 0.0499726005494 | 0.166666666667 | GIPC1 | GIPC1-LHCGR complex |
| CORUM:6861 | 0.0499726005494 | 0.166666666667 | MMUT | MMAA-MUT complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GIPC1 | CS | 0.068 | 0.35 | bioplex_WMM gupta_WMM fraction |
| MMUT | CS | 0.066 | 0.349 | bioplex_WMM fraction |
| RAD23B | CS | 0.042 | 0.27 | bioplex (RAD23B) bioplex_WMM boldt fraction boldt_WMM treiber_WMM |
| CS | KYNU | 0.023 | 0.205 | fraction treiber_WMM |
| GIPC1 | APIP | 0.02 | 0.188 | bioplex (APIP) fraction |
| RAD23B | GIPC1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| RAD23B | APIP | 0.007 | 0.007 | bioplex (APIP) bioplex_WMM |
| GIPC1 | MMUT | 0.006 | 0.004 | bioplex_WMM WMM_only |
| CS | APIP | 0.0 | 0.014 | bioplex (APIP) fraction |
| RAD23B | KYNU | 0.0 | 0.001 | fraction treiber_WMM |
| RAD23B | MMUT | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_01966 has an average edge precision of 0.127 which is ranked 6846 out of all 6965 complexes.
Related Complexes