hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01987
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BUD23 | Probable 18S rRNA (guanine-N(7))-methyltransferase (EC 2.1.1.-) (Bud site selection protein 23 homolog) (Metastasis-related methyltransferase 1) (Williams-Beuren syndrome chromosomal region 22 protein) (rRNA methyltransferase and ribosome maturation factor) | UniProt NCBI |
| TRMT112 | Multifunctional methyltransferase subunit TRM112-like protein (tRNA methyltransferase 112 homolog) | UniProt NCBI |
| TRMT11 | tRNA (guanine(10)-N2)-methyltransferase homolog (EC 2.1.1.-) (tRNA guanosine-2'-O-methyltransferase TRM11 homolog) | UniProt NCBI |
| GALC | Galactocerebrosidase (GALCERase) (EC 3.2.1.46) (Galactocerebroside beta-galactosidase) (Galactosylceramidase) (Galactosylceramide beta-galactosidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070476 | 0.00270494046827 | 0.5 | BUD23 TRMT112 | rRNA (guanine-N7)-methylation |
| GO:0036265 | 0.00811409485621 | 0.5 | BUD23 TRMT112 | RNA (guanine-N7)-methylation |
| REAC:R-HSA-6782315 | 0.00821677913545 | 0.5 | TRMT11 TRMT112 | tRNA modification in the nucleus and cytosol |
| GO:0008173 | 0.011776375189 | 0.75 | TRMT11 TRMT112 BUD23 | RNA methyltransferase activity |
| REAC:R-HSA-6790901 | 0.0177060142151 | 0.5 | BUD23 TRMT112 | rRNA modification in the nucleus and cytosol |
| GO:0016435 | 0.0270421395626 | 0.5 | BUD23 TRMT112 | rRNA (guanine) methyltransferase activity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| BUD23 | TRMT112 | 0.373 | 0.546 | hein_WMM bioplex (BUD23) bioplex_WMM fraction |
| TRMT112 | TRMT11 | 0.134 | 0.405 | bioplex (TRMT11) bioplex_WMM boldt_WMM |
| TRMT11 | GALC | 0.108 | 0.373 | bioplex (TRMT11) bioplex_WMM |
| TRMT112 | GALC | 0.007 | 0.013 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_01987 has an average edge precision of 0.334 which is ranked 4184 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BUD23 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |
| TRMT112 | HuMAP2_01108 HuMAP2_01987 HuMAP2_02860 |
| TRMT11 | HuMAP2_01987 HuMAP2_02860 HuMAP2_04989 |
| GALC | HuMAP2_01987 HuMAP2_02860 HuMAP2_04989 |