hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_01995
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DNAJC2 | DnaJ homolog subfamily C member 2 (M-phase phosphoprotein 11) (Zuotin-related factor 1) [Cleaved into: DnaJ homolog subfamily C member 2, N-terminally processed] | UniProt NCBI |
| EIF2A | Eukaryotic translation initiation factor 2A (eIF-2A) (65 kDa eukaryotic translation initiation factor 2A) [Cleaved into: Eukaryotic translation initiation factor 2A, N-terminally processed] | UniProt NCBI |
| HSPA14 | Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) | UniProt NCBI |
| NFAM1 | NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1) | UniProt NCBI |
| FKBP3 | Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase) | UniProt NCBI |
| CUTC | Copper homeostasis protein cutC homolog | UniProt NCBI |
| PRC1 | Protein regulator of cytokinesis 1 | UniProt NCBI |
| EDF1 | Endothelial differentiation-related factor 1 (EDF-1) (Multiprotein-bridging factor 1) (MBF1) | UniProt NCBI |
| ZNF598 | E3 ubiquitin-protein ligase ZNF598 (EC 2.3.2.27) (Zinc finger protein 598) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0051083 | 0.0126230555186 | 0.25 | DNAJC2 HSPA14 | 'de novo' cotranslational protein folding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HSPA14 | DNAJC2 | 0.967 | 0.877 | hein_WMM bioplex (DNAJC2) bioplex_WMM hein (HSPA14) fraction |
| DNAJC2 | EIF2A | 0.691 | 0.715 | bioplex_WMM gupta_WMM fraction |
| HSPA14 | EIF2A | 0.665 | 0.701 | youn_WMM gupta_WMM fraction |
| DNAJC2 | EDF1 | 0.159 | 0.416 | gupta_WMM fraction |
| EIF2A | FKBP3 | 0.148 | 0.41 | bioplex_WMM youn_WMM gupta_WMM fraction |
| EDF1 | EIF2A | 0.098 | 0.358 | bioplex_WMM youn_WMM gupta_WMM fraction |
| DNAJC2 | ZNF598 | 0.082 | 0.351 | fraction |
| HSPA14 | NFAM1 | 0.057 | 0.324 | bioplex (NFAM1) bioplex_WMM |
| EDF1 | ZNF598 | 0.035 | 0.264 | youn_WMM gupta_WMM fraction |
| DNAJC2 | FKBP3 | 0.029 | 0.232 | bioplex_WMM gupta_WMM fraction |
| HSPA14 | FKBP3 | 0.026 | 0.22 | gupta_WMM fraction |
| HSPA14 | PRC1 | 0.022 | 0.205 | fraction |
| DNAJC2 | PRC1 | 0.022 | 0.196 | fraction |
| HSPA14 | EDF1 | 0.021 | 0.192 | youn_WMM gupta_WMM fraction |
| EDF1 | CUTC | 0.02 | 0.185 | youn_WMM fraction |
| EDF1 | PRC1 | 0.008 | 0.082 | gupta_WMM fraction |
| EIF2A | ZNF598 | 0.007 | 0.009 | youn_WMM gupta_WMM WMM_only |
| ZNF598 | FKBP3 | 0.007 | 0.003 | youn_WMM gupta_WMM WMM_only |
| HSPA14 | ZNF598 | 0.007 | 0.003 | youn_WMM WMM_only |
| ZNF598 | PRC1 | 0.007 | 0.001 | gupta_WMM WMM_only |
| EIF2A | PRC1 | 0.004 | 0.012 | gupta_WMM fraction |
| PRC1 | FKBP3 | 0.004 | 0.011 | gupta_WMM fraction |
| ZNF598 | CUTC | 0.003 | 0.007 | fraction |
| DNAJC2 | CUTC | 0.003 | 0.018 | fraction |
| EDF1 | FKBP3 | 0.0 | 0.001 | bioplex_WMM youn_WMM gupta_WMM fraction |
Images
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Complex HuMAP2_01995 has an average edge precision of 0.232 which is ranked 5661 out of all 6965 complexes.
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